Complement C2

Complement C2 Informations sur la molécule

Nom anglais	Complement C2	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	1	Alias de la cible	C3/C5 convertase
Phase de R&D la plus avancée	Phase 3 Clinical

Nom anglais	Complement C2
Alias de la cible	C3/C5 convertase
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	1
Phase de R&D la plus avancée	Phase 3 Clinical

Complement C2 Liste de produits

Attribut
Protein (8)
Bibliothèque de produits
En ligne (8)
Espèces
Human (1)Cynomolgus (2)Canine (1)Rat (1)Porcine (1)Rabbit (1)Mouse (1)
Étiquette
His Tag (3)His Tag & Avi Tag (5)
Marqueur
Unconjugated (3)Biotin-labeled (5)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT CO2-H52H7	Human	HEK293	Human Complement C2 Protein, His Tag (MALS verified) (active enzyme)	Ajouter au panier
HOT CO2-C52H8	Cynomolgus	HEK293	Cynomolgus Complement C2 Protein, His Tag (active enzyme)	Ajouter au panier
HOT CO2-R82E6	Rat	HEK293	Biotinylated Rat Complement C2 Protein, His,Avitag™ (active enzyme)	Ajouter au panier
CO2-M52H3	Mouse	HEK293	Mouse Complement C2 Protein, His Tag, low endotoxin (MALS verified)	Ajouter au panier
CO2-C82E7	Cynomolgus	HEK293	Biotinylated Cynomolgus Complement C2 Protein, His,Avitag™ (active enzyme, MALS verified)	Ajouter au panier
CO2-D82E4	Canine	HEK293	Biotinylated Canine Complement C2 Protein, His,Avitag™ (active enzyme)	Ajouter au panier
CO2-D82E5	Porcine	HEK293	Biotinylated Porcine Complement C2 Protein, His,Avitag™ (active enzyme)	Ajouter au panier
CO2-R82E3	Rabbit	HEK293	Biotinylated Rabbit Complement C2 Protein, His,Avitag™ (active enzyme)	Ajouter au panier

Quantité totale8

Complement C2Contexte de la molécule

C2 is a major histocompatibility complex class-III protein. Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase. The lectin (LP) and classical (CP) pathways are two of the three main activation cascades of the complement system. These pathways start with recognition of different pathogen- or danger-associated molecular patterns and include identical steps of proteolytic activation of complement component C4, formation of the C3 proconvertase C4b2, followed by cleavage of complement component C2 within C4b2 resulting in the C3 convertase C4b2a.

Complement C2Alias de la molécule

C2,Complement C2,Complement Component C2

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
Empasiprubart	ARGX-117	Phase 3 Clinical	Argenx Se, Broteio Pharma BV	Coronavirus Disease 2019 (COVID-19); Delayed Graft Function; Dermatomyositis; Motor Neuron Disease; Multifocal Motor Neuropathy; Myasthenia Gravis; Myositis; Polyneuropathies; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	Details