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Complement C3

Complement C3 Overview

English NameComplement C3Approved Drugs1
Drugs in Clinical Trials14Target SynonymComplement C3，Complement Component C3a，Epididymis Secretory Sperm Binding Protein Li 62p，C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1，C3bc，C3adesArg，C3，Complement Component C3b，Complement Component 3，C3a Anaphylatoxin，Prepro-C3，CPAMD1，Acylation-Stimulating Protein Cleavage Product，HEL-S-62p，AHUS5，ARMD9，ASP，C3a，C3b
Highest Development StageApproved
English NameComplement C3
Target SynonymComplement C3，Complement Component C3a，Epididymis Secretory Sperm Binding Protein Li 62p，C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1，C3bc，C3adesArg，C3，Complement Component C3b，Complement Component 3，C3a Anaphylatoxin，Prepro-C3，CPAMD1，Acylation-Stimulating Protein Cleavage Product，HEL-S-62p，AHUS5，ARMD9，ASP，C3a，C3b
Approved Drugs1
Drugs in Clinical Trials14
Highest Development StageApproved

Complement C3 Product List

  • Product Category

    Protein (5)Kits (1)

  • Product Status

    Launched (6)

  • Species

    Human (4)Mouse (1)Cynomolgus (1)

  • Tag

    His Tag (3)His Tag & Avi Tag (1)Fc Tag (1)- (1)

  • Conjugate

    Unconjugated (4)Biotin-labeled (1)- (1)

Total: 6
  • 1

Complement C3 Background

C3 is the major complement component serum. It is mainly synthesized by macrophages and liver. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. It is cleaved into two fragments, C3a and C3b. C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Complement C3 Synonyms

Complement C3,CPAMD1
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