CX3CL1

CX3CL1 Informations sur la molécule

Nom anglais	C-X3-C motif chemokine ligand 1	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	1	Alias de la cible	Small Inducible Cytokine Subfamily D (Cys-X3-Cys)， Member 1 (Fractalkine， Neurotactin)，Small Inducible Cytokine Subfamily D (Cys-X3-Cys)， Member-1，CX3CL1，Small-inducible cytokine D1，FKN，Fractalkine，A-152E5.2，C-X3-C Motif Chemokine Ligand 1，Chemokine (C-X3-C Motif) Ligand 1，CX3C Membrane-Anchored Chemokine，C-X3-C Motif Chemokine 1，Neurotactin，SCYD1，NTT，C3Xkine，ABCD-3，CXC3C，CXC3，NTN，Chemokine CX3CL1
Phase de R&D la plus avancée	Phase 2 Clinical

Nom anglais	C-X3-C motif chemokine ligand 1
Alias de la cible	Small Inducible Cytokine Subfamily D (Cys-X3-Cys)， Member 1 (Fractalkine， Neurotactin)，Small Inducible Cytokine Subfamily D (Cys-X3-Cys)， Member-1，CX3CL1，Small-inducible cytokine D1，FKN，Fractalkine，A-152E5.2，C-X3-C Motif Chemokine Ligand 1，Chemokine (C-X3-C Motif) Ligand 1，CX3C Membrane-Anchored Chemokine，C-X3-C Motif Chemokine 1，Neurotactin，SCYD1，NTT，C3Xkine，ABCD-3，CXC3C，CXC3，NTN，Chemokine CX3CL1
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	1
Phase de R&D la plus avancée	Phase 2 Clinical

CX3CL1 Liste de produits

Attribut
Protein (4)
Bibliothèque de produits
En ligne (4)
Espèces
Human (3)Cynomolgus (1)
Étiquette
His Tag (3)His Tag & Avi Tag (1)
Marqueur
Biotin-labeled (2)Unconjugated (2)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT CX1-H8221	Human	HEK293	Biotinylated Human CX3CL1 Protein, His Tag, ultra sensitivity (primary amine labeling)	Ajouter au panier
CX1-H5221	Human	HEK293	Human CX3CL1 / Fractalkine Protein, His Tag	Ajouter au panier
CX1-H82E6	Human	HEK293	Biotinylated Human CX3CL1 Protein, His,Avitag™	Ajouter au panier
CX1-C5222	Cynomolgus	HEK293	Cynomolgus CX3CL1 / Fractalkine Protein, His Tag (MALS verified)	Ajouter au panier

Quantité totale4

Demande de produit

CX3CL1Contexte de la molécule

Fractalkine is also known as C-X3-C motif chemokine 1 (CX3CL1) and neurotactin. Fractalkine is a large cytokine protein of 373 amino acids, it contains multiple domains and is the only known member of the CX3C chemokine family. Fractalkine is found commonly throughout the brain, particularly in neural cells, and its receptor is known to be present on microglial cells. It has also been found to be essential for microglial cell migration. CX3CL1 is also up-regulated in the hippocampus during a brief temporal window following spatial learning, the purpose of which may be to regulate glutamate-mediated neurotransmission tone. This indicates a possible role for the chemokine in the protective plasticity process of synaptic scaling.