DLL1

DLL1 Informations sur la molécule

Nom anglais	Delta Like Canonical Notch Ligand 1	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0	Alias de la cible	Delta Like Canonical Notch Ligand 1，Drosophila Delta Homolog 1，Delta-Like Protein 1，H-Delta-1，Epididymis Secretory Sperm Binding Protein，Delta (Drosophila)-Like 1，Delta-Like 1 (Drosophila)，DELTA1，NEDBAS，Delta1，Delta，DL1，Drosophila Delta homolog 1 (Delta1; H-Delta-1)
Phase de R&D la plus avancée	Preclinical

Nom anglais	Delta Like Canonical Notch Ligand 1
Alias de la cible	Delta Like Canonical Notch Ligand 1，Drosophila Delta Homolog 1，Delta-Like Protein 1，H-Delta-1，Epididymis Secretory Sperm Binding Protein，Delta (Drosophila)-Like 1，Delta-Like 1 (Drosophila)，DELTA1，NEDBAS，Delta1，Delta，DL1，Drosophila Delta homolog 1 (Delta1; H-Delta-1)
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0
Phase de R&D la plus avancée	Preclinical

DLL1 Liste de produits

Attribut
Protein (3)Cell Grade Beads (2)
Bibliothèque de produits
En ligne (5)
Espèces
Human (3)- (2)
Étiquette
His Tag (1)His Tag & Avi Tag (1)- (2)Fc Tag (1)
Marqueur
Unconjugated (2)Biotin-labeled (1)- (2)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT DL1-H52H8	Human	HEK293	Human DLL1 / Delta1 Protein, His Tag, premium grade	Ajouter au panier
HOT DL1-H82E5	Human	HEK293	Biotinylated Human DLL1 / Delta1 Protein, His,Avitag™, premium grade	Ajouter au panier
HOT MBS-C040	-	-	ActiveMax® Human DLL1 μBeads, premium grade (for cells, 5.5μm)	Ajouter au panier
DL1-H5259	Human	HEK293	Human DLL1 / Delta1 Protein, Fc Tag, premium grade	Ajouter au panier
MBS-C041	-	-	ActiveMax® Human DLL1 μBeads, premium grade (for cells, 20 μm)	Ajouter au panier

Quantité totale5

DLL1Contexte de la molécule

Delta-like protein 1 (DLL1) is also known as Drosophila Delta homolog 1 (Delta1 or H-Delta-1), which contains one DSL domain and eight EGF-like domains. DLL1 is ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. As for expression, DLL1 is expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. Furthermore, DLL1 acts as a ligand for Notch receptors. Also, DLL1 can block the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.