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Page d'accueilToutes les moléculesDM-4
DM-4
DM-4 Liste de produits
- Attribut
Antibody (3)
- Bibliothèque de produits
En ligne (3)
- Espèces
Rabbit (3)
- Étiquette
- (3)
- Marqueur
Unconjugated (3)
| Numéro de produit | Espèces | Système d'expression | Description du produit | Structure protéique | Pureté | Caractéristiques | Pré-commande/Commande |
|---|---|---|---|---|---|---|---|
 Rabbit | HEK293 | Monoclonal Anti-DM-4 Antibody, Rabbit IgG (M1A02) |  |  Ajouter au panier | |||
| Rabbit | HEK293 | Monoclonal Anti-DM-4 Antibody, Rabbit IgG (M1A09) | | Ajouter au panier | |||
| Rabbit | HEK293 | Monoclonal Anti-DM-4 Antibody, Rabbit IgG (M1H02) | | Ajouter au panier |
Quantité totale3
- 1
DM-4Contexte de la molécule
DM4 (also known as ravtansine or soravtansine) is a maytansinoid derivative that serves as a potent cytotoxic payload in antibody-drug conjugates (ADCs). It functions by inhibiting tubulin polymerization, arresting cell division, and inducing apoptosis in tumor cells. Structurally modified from DM1, DM4 enhances conjugation compatibility with linkers and has been used in several clinical ADC drugs, including mirvetuximab soravtansine for ovarian cancer treatment.
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