EMMPRIN
EMMPRIN Informations sur la molécule
| Nom anglais | Basigin | Nombre de médicaments commercialisés | 1 |
| Nombre de médicaments cliniques | 4 | Alias de la cible | BSG，Extracellular matrix metalloproteinase inducer，UNQ6505/PRO21383，Basigin (Ok Blood Group)，Tumor Cell-Derived Collagenase Stimulatory Factor，Leukocyte Activation Antigen M6，Collagenase Stimulatory Factor，Basigin，5F7，Ok Blood Group，CD147 Antigen，EMPRIN，CD147，OK，TCSF，EMMPRIN，SLC7A11，OK blood group antigen |
| Phase de R&D la plus avancée | Approved | ||
| Nom anglais | Basigin |
| Alias de la cible | BSG，Extracellular matrix metalloproteinase inducer，UNQ6505/PRO21383，Basigin (Ok Blood Group)，Tumor Cell-Derived Collagenase Stimulatory Factor，Leukocyte Activation Antigen M6，Collagenase Stimulatory Factor，Basigin，5F7，Ok Blood Group，CD147 Antigen，EMPRIN，CD147，OK，TCSF，EMMPRIN，SLC7A11，OK blood group antigen |
| Nombre de médicaments commercialisés | 1 |
| Nombre de médicaments cliniques | 4 |
| Phase de R&D la plus avancée | Approved |
EMMPRIN Liste de produits
- Attribut
Protein (6)
- Bibliothèque de produits
En ligne (6)
- Espèces
Human (4)Mouse (1)Cynomolgus (1)
- Étiquette
His Tag (3)Fc Tag (1)His Tag & Avi Tag (2)
- Marqueur
Unconjugated (3)Biotin-labeled (2)FITC Labeled (1)
| Numéro de produit | Espèces | Système d'expression | Description du produit | Structure protéique | Pureté | Caractéristiques | Pré-commande/Commande |
|---|---|---|---|---|---|---|---|
HOT CD7-H5222 |  Human | HEK293 | Human EMMPRIN / CD147 Protein, His Tag (MALS verified) |  |  |  |  Ajouter au panier |
HOT CD7-H82E0 | Human | HEK293 | Biotinylated Human EMMPRIN / CD147 Protein, Avitag™,His Tag (MALS verified) |  | | | Ajouter au panier |
HOT CD7-M82E8 |  Mouse | HEK293 | Biotinylated Mouse EMMPRIN / CD147 Protein, His,Avitag™ (MALS verified) |  | | Ajouter au panier | |
| Human | HEK293 | Human EMMPRIN / CD147 Protein, Fc Tag |  | | | Ajouter au panier | |
| Human | HEK293 | FITC-Labeled Human EMMPRIN / CD147 Protein, His Tag |  | | | Ajouter au panier | |
 Cynomolgus | HEK293 | Cynomolgus EMMPRIN / CD147 Protein, His Tag (MALS verified) |  | | | Ajouter au panier |
Quantité totale6
- 1
EMMPRINContexte de la molécule
CD147, also known as Basigin (BSG), or extracellular matrix metalloproteinase inducer (EMMPRIN). The human basigin protein contains 269 amino acids that form two heavily glycosylated C2 type immunoglobulin-like domains at the N-terminal extracellular portion. A second form of basigin has also been characterized that contains one additional immunoglobulin-like domain in its extracellular portion. As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, basigin is thought also to play a role in intercellular recognition and regulate several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. Basigin is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins.
EMMPRINAlias de la molécule
Basigin,BSG,5F7,CD147,EMMPRIN,M6,OK,TCSF
Informations sur les médicaments cliniques
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Indication | Essai clinique |
|---|---|---|---|---|---|
| Mertuzumab | Phase 3 Clinical | Institute Of Medicine Fourth Military Medical University, Jiangsu Pacific Minok Biopharmaceutical Co., Ltd. | Carcinoma, Non-Small-Cell Lung; Coronavirus Disease 2019 (COVID-19) | Details | |
| Meplazumab | HI6H8 | Phase 3 Clinical | Institute Of Medicine Fourth Military Medical University, Jiangsu Pacific Minok Biopharmaceutical Co., Ltd. | Coronavirus Disease 2019 (COVID-19); Malaria; Malaria, Falciparum; Post-Acute COVID-19 Syndrome | Details |
| humanized ADCC cHAb18 antibody (Pacific Meinuoke/Fourth Military Medical University) | Phase 1 Clinical | Air Force Medical University | Carcinoma, Non-Small-Cell Lung | Details | |
| CD147-CAR T cell therapy (Peking University People's Hospital) | Phase 1 Clinical | Peking University People'S Hospital | Lymphoma, T-Cell | Details |
Informations sur les médicaments commercialisés
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Plus ancien nom de marque | Pays d'approbation le plus ancien | Indication la plus ancienne | Société d'approbation la plus ancienne | Date d'approbation la plus ancienne | Indication | Essai clinique |
|---|---|---|---|---|---|---|---|---|---|---|
| Iodine[131I] Metuximab | Approved | Chengdu Huasun Biotechnology Co Ltd | Licartin, 利卡汀 | Mainland China | Carcinoma, Hepatocellular | Chengdu Huasun Biotechnology Co Ltd | 2006-10-12 | Carcinoma, Hepatocellular | Details |
- Informations sur la molécule
- Liste de produits
- Informations sur les médicaments commercialisés
- Informations sur les médicaments cliniques