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Fc gamma RI / CD64

Fc gamma RI / CD64 Informations sur la molécule

Nom anglaisHigh affinity immunoglobulin gamma Fc receptor INombre de médicaments commercialisés0
Nombre de médicaments cliniques0Alias de la cibleIgG Fc Receptor I,FcgammaRIa,High Affinity Immunoglobulin Gamma Fc Receptor I,Fc-Gamma Receptor I A1,CD64 Antigen,CD64A,CD64,FCG1,FCGR1,IGFR1,FcRI,Fc-gamma RIA,Fc-gamma RI,Fc Fragment Of IgG Receptor Ia,Fc Fragment Of IgG, High Affinity Ia, Receptor (CD64),Fc Gamma Receptor Ia,FCGR1A,Fc Fragment Of IgG, High Affinity Ia, Receptor For (CD64)
Phase de R&D la plus avancéePreclinical
Nom anglaisHigh affinity immunoglobulin gamma Fc receptor I
Alias de la cibleIgG Fc Receptor I,FcgammaRIa,High Affinity Immunoglobulin Gamma Fc Receptor I,Fc-Gamma Receptor I A1,CD64 Antigen,CD64A,CD64,FCG1,FCGR1,IGFR1,FcRI,Fc-gamma RIA,Fc-gamma RI,Fc Fragment Of IgG Receptor Ia,Fc Fragment Of IgG, High Affinity Ia, Receptor (CD64),Fc Gamma Receptor Ia,FCGR1A,Fc Fragment Of IgG, High Affinity Ia, Receptor For (CD64)
Nombre de médicaments commercialisés0
Nombre de médicaments cliniques0
Phase de R&D la plus avancéePreclinical

Fc gamma RI / CD64Contexte de la molécule

Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. High affinity immunoglobulin gamma Fc receptor I is also known as FCGR1A, FCG1, FCGR1, CD64 and IGFR1, is a type of integral membrane glycoprotein that binds monomeric IgG-type antibodies with high affinity, which belongs to the immunoglobulin superfamily or FCGR1 family. FCGR1A / CD64 contains 3 Ig-like C2-type (immunoglobulin-like) domains. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells.

Fc gamma RI / CD64Alias de la molécule

FCGR1A,FCG1,FCGR1,IGFR1,CD64,CD64A,FCRI

Avis sur les produits

  • g***t2025-11-29
    0Mettre un like
    Very good product for SPR analyses with antibodies
  • H***n2023-05-03
    0Mettre un like
    I used Acro's Fc gamma receptors to build several new antibody binding assays. The proteins arrived promptly, sometimes within a few days of placing the orders. The proteins were also high quality, with no background or issues with stability. I have continued to use them for months with no issues. These produced high quality and robust data with minimal assay development. I would highly recommend this product.
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