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FGF19

FGF19 Overview

English Name	Fibroblast growth factor 19	Approved Drugs	0
Drugs in Clinical Trials	2	Target Synonym	FGF-19
Highest Development Stage	Phase 2 Clinical

English Name	Fibroblast growth factor 19
Target Synonym	FGF-19
Approved Drugs	0
Drugs in Clinical Trials	2
Highest Development Stage	Phase 2 Clinical

FGF19 Product List

Product Category
Protein (3)
Product Status
Launched (3)
Species
Human (3)
Tag
Fc Tag (1)His Tag (1)Mouse IgG Fc Tag (1)
Conjugate
Unconjugated (3)

Cat. No.	Species	Host	Product Description
FG9-H51H3	Human	E. coli	Human FGF19 Protein, His Tag
FG9-H5253	Human	HEK293	Human FGF19 Protein, Fc Tag
FG9-H5254	Human	HEK293	Human FGF19 Protein, Mouse IgG2a Fc Tag

Total: 3

FGF19 Background

Fibroblast growth factor (FGF)19 is the first members of a new subfamily of FGFs and could act as hormones. During fetal life, FGF15/19 is involved in organogenesis, affecting the development of the ear, eye, heart, and brain. FGFs–FGFRs are involved in regulation of many biological processes such as embryonic development, cell proliferation, differentiation, and tissue repair. The dysregulation of FGF–FGFR was observed in different types of diseases, disorders, and cancers. Notably, aberrant expression of FGF19/FGFR4 contributes to Hepatocellular Carcinoma progression.

FGF19 Synonyms

FGF19,FGF-19,Fibroblast growth factor 19

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Aldafermin	M-70; NGM-282; M70; NGM282	Phase 2 Clinical	NGM Biopharmaceuticals Inc	Bile acid malabsorption (BAM); Cholangitis, Sclerosing; Constipation; Diabetes Mellitus; Diarrhea; Fibrosis; Hepatic Insufficiency; Irritable Bowel Syndrome; Liver Cirrhosis, Biliary; Malabsorption Syndromes; Metabolic Dysfunction-Associated Steatotic Liver Disease; Renal Insufficiency	Details
HH-009		Phase 1 Clinical	Huahui Health Ltd	Neoplasms; Solid tumours	Details

Product Reviews

M***i2023-02-08
1People Like
Human FGF19 Protein, Fc Tag
Awesome.The product quality was good ,and great technical service and I received the product on time.