GITR Informations sur la molécule
Molecule Name
Glucocorticoid-induced tumor necrosis factor receptor-related protein
Alias de la molécule
AITR,GITR,TNFRSF18,CD357
Drug Development Progress
Nombre de médicaments cliniques4
Nombre de médicaments commercialisés0
Phase de R&D la plus avancéePhase 2 Clinical
Alias de la cible
TNFRSF18，TNF Receptor Superfamily Activation-Inducible Protein，ENERGEN，GITR-D，Tumor Necrosis Factor Receptor Superfamily Member 18，CD357 Antigen，Activation-Inducible TNFR Family Receptor，AITR，CD357，GITR，Glucocorticoid-Induced TNFR-Related Protein，Tumor Necrosis Factor Receptor Superfamily， Member 18，TNF Receptor Superfamily Member 18
Contexte de la molécule
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
GITR Liste de produits
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1***32019-09-27I have been using Acro's products for a long time. Whenever there is some concerns on product or technical support is needed, it always gets solved in time. I used the GITR protein for SPR experiments. I have done 6 concentration gradients, and the fitted curve was still very good. The data also met my expectations. I hope we will continue having a good cooperation with ACRO moving forward.