GITR Ligand

GITR Ligand Informations sur la molécule

Nom anglais	Tumor necrosis factor ligand superfamily member 18	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0	Alias de la cible	AITRL，GITRL，TL6，UNQ149，PRO175，Glucocorticoid-induced TNF-related ligand，hGITRL，Activation-inducible TNF-related ligand
Phase de R&D la plus avancée	Preclinical

Nom anglais	Tumor necrosis factor ligand superfamily member 18
Alias de la cible	AITRL，GITRL，TL6，UNQ149，PRO175，Glucocorticoid-induced TNF-related ligand，hGITRL，Activation-inducible TNF-related ligand
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0
Phase de R&D la plus avancée	Preclinical

GITR Ligand Liste de produits

Attribut
Protein (6)
Bibliothèque de produits
En ligne (6)
Espèces
Human (5)Mouse (1)
Étiquette
Fc Tag (3)Avi Tag & Fc Tag (1)His Tag (2)
Marqueur
Unconjugated (5)Biotin-labeled (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT GIL-H5249	Human	HEK293	Human GITR Ligand / TNFSF18 Protein, His Tag	Ajouter au panier
HOT GIL-H524a	Human	HEK293	Human GITR Ligand / TNFSF18 Protein, His Tag, active trimer (MALS verified)	Ajouter au panier
HOT GIL-H5263	Human	HEK293	Human GITR Ligand / TNFSF18 Protein, Fc Tag, active trimer (MALS verified)	Ajouter au panier
GIL-H526a	Human	HEK293	Human GITR Ligand / TNFSF18 Protein, Fc Tag	Ajouter au panier
GIL-H82F8	Human	HEK293	Biotinylated Human GITR Ligand / TNFSF18 Protein, Avitag™,Fc Tag	Ajouter au panier
GIL-M526x	Mouse	HEK293	Mouse GITR Ligand / TNFSF18 Protein, Fc Tag	Ajouter au panier

Quantité totale6

GITR LigandContexte de la molécule

Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.