GM-CSF R alpha

GM-CSF R alpha Informations sur la molécule

Nom anglais	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	4	Alias de la cible	GM-CSF-R-alpha，GMCSFR-alpha，GMR-alpha，CD116，Colony Stimulating Factor 2 Receptor Subunit Alpha，Colony Stimulating Factor 2 Receptor， Alpha， Low-Affinity (Granulocyte-Macrophage)，CSF2R，CSF2RAX，CSF2RAY，CSF2RX，CSF2RY，GM-CSF Receptor Alpha Subunit，GMCSFR，GMR，Granulocyte-Macrophage Colony-Stimulating Factor Receptor Alpha Chain，SMDP4，Colony Stimulating Factor 2 Receptor Alpha Subunit，CDw116，CD116 Antigen，Alpha-GM-CSF Receptor，AlphaGMR
Phase de R&D la plus avancée	Phase 3 Clinical

Nom anglais	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
Alias de la cible	GM-CSF-R-alpha，GMCSFR-alpha，GMR-alpha，CD116，Colony Stimulating Factor 2 Receptor Subunit Alpha，Colony Stimulating Factor 2 Receptor， Alpha， Low-Affinity (Granulocyte-Macrophage)，CSF2R，CSF2RAX，CSF2RAY，CSF2RX，CSF2RY，GM-CSF Receptor Alpha Subunit，GMCSFR，GMR，Granulocyte-Macrophage Colony-Stimulating Factor Receptor Alpha Chain，SMDP4，Colony Stimulating Factor 2 Receptor Alpha Subunit，CDw116，CD116 Antigen，Alpha-GM-CSF Receptor，AlphaGMR
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	4
Phase de R&D la plus avancée	Phase 3 Clinical

GM-CSF R alpha Liste de produits

Attribut
Protein (3)
Bibliothèque de produits
En ligne (3)
Espèces
Human (2)Mouse (1)
Étiquette
His Tag (2)Fc Tag (1)
Marqueur
Unconjugated (3)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT GRA-H52H7	Human	HEK293	Human GM-CSF R alpha Protein, His Tag (SPR verified)	Ajouter au panier
GRA-H5255	Human	HEK293	Human GM-CSF R alpha Protein, Fc Tag	Ajouter au panier
GMA-M52H3	Mouse	HEK293	Mouse GM-CSF R alpha Protein, His Tag	Ajouter au panier

Quantité totale3

GM-CSF R alphaContexte de la molécule

GM-CSF R alpha(Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor α-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.

GM-CSF R alphaAlias de la molécule

GM-CSF R alpha,GM-CSF-R-alpha,GMCSFR-alpha,GMR-alpha,CSF2RA,CSF2R,CSF2RY,CDw116,CD116

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
Mavrilimumab	CAM-3001; KPL-301; GM-CSFR; CAM3001	Phase 3 Clinical	Csl Ltd	Arthritis, Rheumatoid; Coronavirus Disease 2019 (COVID-19); Giant Cell Arteritis; Pneumonia	Details
Anti-GMR CAR T-cell Therapy		Phase 2 Clinical	Kyoto Prefectural University Of Medicine, Shinshu University School of Medicine	Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Juvenile	Details
CSF2RA gene-corrected macrophages(University of South Florida)		Phase 2 Clinical	Russian Academy Of Medical Sciences	Pulmonary Alveolar Proteinosis	Details
STSA-1005	STSA-1005; STSA1005	Phase 1 Clinical	Staidson(Beijing) Biopharmaceuticals Co Ltd	Coronavirus Disease 2019 (COVID-19)	Details