GPR75

GPR75 Liste de produits

  • Attribut

    Cell (1)Protein (3)

  • Bibliothèque de produits

    En ligne (4)

  • Espèces

    Human (4)

  • Étiquette

    - (2)His Tag & Flag Tag (1)His Tag & Avi Tag & Flag Tag (1)

  • Marqueur

    - (1)Unconjugated (2)Biotin-labeled (1)

GPR75Contexte de la molécule

G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.

Informations sur les médicaments cliniques

Nom anglaisCode de recherchePhase de R&DEntrepriseIndicationEssai clinique
bbT-369bbT-369Phase 2 ClinicalBluebird Bio IncLymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin
Details

Avis sur les produits

  • H***e2025-11-02
    0Mettre un like
    We verified that the cell line shows strong GPR75 expression by flow cytometry. The Acro team was very responsive and provided clear, helpful answers to our technical questions about the cell line’s characteristics.
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  • Informations sur les médicaments cliniques