GUCY2D

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GUCY2D Informations sur la molécule

Molecule Name

Retinal guanylyl cyclase 1

Alias de la molécule

GUCY2D,Retinal guanylyl cyclase 1,RETGC-1,CORD6,GUC1A4,GUC2D,ROS-GC

Drug Development Progress

Nombre de médicaments cliniques1

Nombre de médicaments commercialisés0

Phase de R&D la plus avancéePhase 2 Clinical

Alias de la cible

RETGC-1，CG-E，Guanylate cyclase 2D， retinal，Rod outer segment membrane guanylate cyclase (ROS-GC)，CORD6，GUC1A4，GUC2D，RETGC，RETGC1

Contexte de la molécule

GUCY2D also known as CORD6, GUC1A4, GUC2D ROS-GC and RETGC-1, belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane.