IGF-II R

IGF-II R Informations sur la molécule

Nom anglais	Insulin-like growth factor II receptor	Nombre de médicaments commercialisés	1
Nombre de médicaments cliniques	0	Alias de la cible	Insulin-like growth factor 2 receptor，IGF-II receptor，CD222，Insulin Like Growth Factor 2 Receptor，M6P/IGF2R，M6P/IGF2 receptor，CI Man-6-P receptor，Insulin-like growth factor II receptor，IGF2R，300 KDa Mannose 6-Phosphate Receptor，MPR 300，MPRI，Cation-Independent Mannose-6-Phosphate Receptor，Cation-Independent Mannose-6 Phosphate Receptor，CD222 Antigen，CI-M6PR，MPR300，CI-MPR，CIMPR，M6P-R，MPR1，M6PR，Receptor， IGF Type 2
Phase de R&D la plus avancée	Approved

Nom anglais	Insulin-like growth factor II receptor
Alias de la cible	Insulin-like growth factor 2 receptor，IGF-II receptor，CD222，Insulin Like Growth Factor 2 Receptor，M6P/IGF2R，M6P/IGF2 receptor，CI Man-6-P receptor，Insulin-like growth factor II receptor，IGF2R，300 KDa Mannose 6-Phosphate Receptor，MPR 300，MPRI，Cation-Independent Mannose-6-Phosphate Receptor，Cation-Independent Mannose-6 Phosphate Receptor，CD222 Antigen，CI-M6PR，MPR300，CI-MPR，CIMPR，M6P-R，MPR1，M6PR，Receptor， IGF Type 2
Nombre de médicaments commercialisés	1
Nombre de médicaments cliniques	0
Phase de R&D la plus avancée	Approved

IGF-II R Liste de produits

Attribut
Protein (2)
Bibliothèque de produits
En ligne (2)
Espèces
Human (2)
Étiquette
His Tag (2)
Marqueur
Unconjugated (2)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
IGR-H52H4	Human	HEK293	Human IGF-II R (43-1365) Protein, His Tag (MALS verified)				Ajouter au panier
IGR-H53H3	Human	CHO	Human IGF-II R Protein, His Tag (MALS verified)				Ajouter au panier

Quantité totale2

IGF-II RContexte de la molécule

IGF2R, also known as the cation-independent mannose-6-phosphate receptor, is found ubiquitously in human tissues with a truncated soluble form of the receptor present in the circulation. Full-length, 300-kDa, IGF2R comprises a large N-terminal extracellular region of 15 homologous domains, a single membrane-spanning region and a small cytoplasmic tail. In addition to IGF-II binding, major IGF2R functions include sorting newly synthesized lysosomal enzymes and endocytosis of extracellular lysosomal enzymes. To perform these disparate functions, the extracellular region contains binding sites for IGF-II and phosphomannosyl residues

IGF-II RAlias de la molécule

Cation-independent mannose-6-phosphate receptor,CI Man-6-P receptor,CI-MPR,M6PR,300 kDa mannose 6-phosphate receptor (MPR 300),Insulin-like growth factor 2 receptor,Insulin-like growth factor II receptor (IGF-II receptor),M6P/IGF2 receptor (M6P/IGF2R),CD2

Informations sur les médicaments commercialisés

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Plus ancien nom de marque	Pays d'approbation le plus ancien	Indication la plus ancienne	Société d'approbation la plus ancienne	Date d'approbation la plus ancienne	Indication	Essai clinique
Avalglucosidase alfa	neoGAA; GZ-402666; Neo-rhGAA; NeoGAA	Approved	Genzyme Corp	Nexviazyme, Nexviadyme, 耐而赞	United States	Glycogen Storage Disease Type II	Genzyme Corp	2021-08-06	Glycogen Storage Disease Type II	Details