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IL-1 RAcP

IL-1 RAcP Informations sur la molécule

Nom anglaisInterleukin-1 receptor accessory proteinNombre de médicaments commercialisés0
Nombre de médicaments cliniques8Alias de la cibleInterleukin-1 receptor 3,IL-1RAcP,IL-1 receptor accessory protein,IL-1R-3,C3orf13,Interleukin 1 Receptor Accessory Protein,IL1R3,Interleukin-1 Receptor Accessory Protein Beta,IL-1R3
Phase de R&D la plus avancéePhase 2 Clinical
Nom anglaisInterleukin-1 receptor accessory protein
Alias de la cibleInterleukin-1 receptor 3,IL-1RAcP,IL-1 receptor accessory protein,IL-1R-3,C3orf13,Interleukin 1 Receptor Accessory Protein,IL1R3,Interleukin-1 Receptor Accessory Protein Beta,IL-1R3
Nombre de médicaments commercialisés0
Nombre de médicaments cliniques8
Phase de R&D la plus avancéePhase 2 Clinical

IL-1 RAcPContexte de la molécule

Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.

IL-1 RAcPAlias de la molécule

IL1RAP,IL-1RAcP,C3orf13,IL1R3

Informations sur les médicaments cliniques

Nom anglaisCode de recherchePhase de R&DEntrepriseIndicationEssai clinique
NidanilimabCAN-04Phase 2 ClinicalLund University FoundationBiliary Tract Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Transitional Cell; Colorectal Neoplasms; Leukemia, Myeloid, Acute; Melanoma; Myelodysplastic Syndromes; Pancreatic Neoplasms; Sarcoidosis, Pulmonary; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms
Details
CCTx-001CCTx-001Phase 2 ClinicalAdvesya SASLeukemia, Myeloid, Acute; Myelodysplastic Syndromes
Details
SAR-445399SAR-445399Phase 2 ClinicalSanofiHidradenitis Suppurativa; Immune System Diseases; Inflammation
Details
IBI-3011IBI-3011; IBI3011Phase 1 ClinicalArthritis, Gouty; Gout
Details
Gene modified anti-IL1RAP Chimeric Antigen Receptor T Cells therapy(Shanghai Zhongshan Hospital)Phase 1 ClinicalShanghai Zhongshan HospitalCarcinoma, Hepatocellular
Details
AK-135AK135; AK-135Phase 1 ClinicalPeripheral Nervous System Diseases
Details
DXP-106DXP-106; DXP106Phase 1 ClinicalSinglomics Biopharmaceuticals Co LtdNeoplasms; Solid tumours
Details
GSK-3903371GSK-3903371; BOS-371ClinicalGlaxosmithkline PlcNeoplasms
Details
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