IL-17 RA & IL-17 RC

IL-17 RA & IL-17 RC Overview

English NameInterleukin-17 receptor AApproved Drugs1
Drugs in Clinical Trials1Target SynonymCDw217,IL-17 receptor A,IL17R,IL17RA,Interleukin 17 Receptor A,IL-17RA,Interleukin 17 Receptor,CD217 Antigen,HIL-17R,CANDF5,CD217,IMD51,Interleukin-17 receptor A
Highest Development StageApproved
English NameInterleukin-17 receptor A
Target SynonymCDw217,IL-17 receptor A,IL17R,IL17RA,Interleukin 17 Receptor A,IL-17RA,Interleukin 17 Receptor,CD217 Antigen,HIL-17R,CANDF5,CD217,IMD51,Interleukin-17 receptor A
Approved Drugs1
Drugs in Clinical Trials1
Highest Development StageApproved

IL-17 RA & IL-17 RC Product List

  • Product Category

    Protein (1)Cell (1)

  • Product Status

    Launched (2)

  • Species

    Human (2)

  • Tag

    Fc Tag (1)- (1)

  • Conjugate

    Unconjugated (1)- (1)

Total: 2
  • 1

IL-17 RA & IL-17 RC Background

Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC. Cytokine binding triggers homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter, leading to TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways, ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation.

IL-17 RA & IL-17 RC Synonyms

IL-17 RA & IL-17 RC,IL-17RA & IL-17RC,CD217 & IL-17 RC
  • Overview
  • Product List