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IL-17C

IL-17C Liste de produits

  • Attribut

    Protein (3)

  • Bibliothèque de produits

    En ligne (3)

  • Espèces

    Human (2)Mouse (1)

  • Étiquette

    His Tag & Avi Tag (1)His Tag (2)

  • Marqueur

    Biotin-labeled (1)Unconjugated (2)

Numéro de produitEspècesSystème d'expressionDescription du produitStructure protéiquePuretéCaractéristiquesPré-commande/Commande
HOT
ILC-H52H7
Human
HEK293
Human IL-17C Protein, His Tag
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HOT
ILC-H82E5
Human
HEK293
Biotinylated Human IL-17C Protein, His,Avitag™ (MALS verified)
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HOT
ILC-M52H7
Mouse
HEK293
Mouse IL-17C Protein, His Tag
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Quantité totale3
  • 1

IL-17CContexte de la molécule

Interleukin-17C(IL-17C) is a glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. IL‑17C binds to IL‑17 RE with high affinity and to IL‑17 RA with low affinity, binds to a heterodimer formed by IL17RA and IL17RE. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes.
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