IL-4

IL-4 Overview

English NameInterleukin-4Approved Drugs2
Drugs in Clinical Trials7Target SynonymMGC79402,B-cell stimulatory factor 1,Lymphocyte stimulatory factor 1,IL4,Interleukin 4,B_cell Stimulatory Factor 1,B Cell Growth Factor 1,Binetrakin,Pitrakinra,BSF-1,IL-4,Interleukin 4 Variant 2,BCGF-1,BCGF1,BSF1,Interleukin-4
Highest Development StageApproved
English NameInterleukin-4
Target SynonymMGC79402,B-cell stimulatory factor 1,Lymphocyte stimulatory factor 1,IL4,Interleukin 4,B_cell Stimulatory Factor 1,B Cell Growth Factor 1,Binetrakin,Pitrakinra,BSF-1,IL-4,Interleukin 4 Variant 2,BCGF-1,BCGF1,BSF1,Interleukin-4
Approved Drugs2
Drugs in Clinical Trials7
Highest Development StageApproved

IL-4 Product List

  • Product Category

    Protein (7)Kits (6)

  • Product Status

    Launched (13)

  • Species

    Human (9)Mouse (3)Cynomolgus (1)

  • Tag

    Tag Free (2)His Tag & Avi Tag (1)His Tag (2)Fc Tag (2)- (6)

  • Conjugate

    Unconjugated (6)Biotin-labeled (1)- (6)

Total: 13
  • 1
  • 2

IL-4 Background

Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells). In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.

IL-4 Synonyms

IL4,BCGF1,BSF1

Product Reviews

  • M***e2023-06-15
    3People Like
    We have used this kit to profile compounds. This kit is both reliable and easy to use, and it shipped quickly. The 96 test kit is also amenable to scaling to a 384 well format for additional screening capabilities. In our experience, the customer service at ACRO has always been prompt when inquiring about when items will be restocked and when they have shipped.
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