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IL-5

IL-5 Overview

English NameInterleukin-5Approved Drugs2
Drugs in Clinical Trials7Target SynonymT-cell replacing factor，IL5，Interleukin 5，Eosinophil Differentiation Factor，Colony-Stimulating Factor， Eosinophil，B-Cell Differentiation Factor I，Interleukin-5，IL-5，TRF，Interleukin 5 (Colony-Stimulating Factor， Eosinophil)，B Cell Differentiation Factor I，EDF
Highest Development StageApproved
English NameInterleukin-5
Target SynonymT-cell replacing factor，IL5，Interleukin 5，Eosinophil Differentiation Factor，Colony-Stimulating Factor， Eosinophil，B-Cell Differentiation Factor I，Interleukin-5，IL-5，TRF，Interleukin 5 (Colony-Stimulating Factor， Eosinophil)，B Cell Differentiation Factor I，EDF
Approved Drugs2
Drugs in Clinical Trials7
Highest Development StageApproved

IL-5 Product List

  • Product Category

    Protein (7)Kits (4)

  • Product Status

    Launched (11)

  • Species

    Human (6)Rabbit (1)Mouse (2)Cynomolgus (1)Canine (1)

  • Tag

    His Tag (5)His Tag & Avi Tag (1)- (4)Tag Free (1)

  • Conjugate

    Unconjugated (6)Biotin-labeled (1)- (4)

Total: 11
  • 1
  • 2

IL-5 Background

Interleukin 5 (IL5) is an interleukin produced by type-2 T helper cells and mast cells. IL-5 is a 115-amino acid (in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely interleukin 3 and GM-CSF), this glycoprotein in its active form is a homodimer. Interleukin-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma, wherein a large increase in the number of circulating, airway tissue, and induced sputum eosinophils have been observed. Given the high concordance of eosinophils and, in particular, allergic asthma pathology, it has been widely speculated that eosinophils have an important role in the pathology of this disease. Drugs that target IL-5 are mepolizumab and reslizumab.

IL-5 Synonyms

IL-5,TRF,IL5,Interleukin-5
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