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IL-7 R alpha & TSLP R
IL-7 R alpha & TSLP R Informations sur la molécule
| Nom anglais | Interleukin-7 receptor subunit alpha | Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 8 | Alias de la cible | Interleukin-7 receptor subunit alpha，Interleukin 7 Receptor Isoform H5-6，CDw127，IL-7R subunit alpha，IL-7RA，IL-7 receptor subunit alpha，CD127 Antigen，IL-7R-Alpha，Interleukin 7 Receptor Alpha Chain，CD127，IL7RA，ILRA，Interleukin-7 Receptor alpha Subunit |
| Phase de R&D la plus avancée | Phase 2 Clinical | ||
| Nom anglais | Interleukin-7 receptor subunit alpha |
| Alias de la cible | Interleukin-7 receptor subunit alpha，Interleukin 7 Receptor Isoform H5-6，CDw127，IL-7R subunit alpha，IL-7RA，IL-7 receptor subunit alpha，CD127 Antigen，IL-7R-Alpha，Interleukin 7 Receptor Alpha Chain，CD127，IL7RA，ILRA，Interleukin-7 Receptor alpha Subunit |
| Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 8 |
| Phase de R&D la plus avancée | Phase 2 Clinical |
IL-7 R alpha & TSLP R Liste de produits
- Attribut
Protein (3)Cell (1)Kits (1)
- Bibliothèque de produits
En ligne (5)
- Espèces
Human (4)Mouse (1)
- Étiquette
Fc Tag (3)- (2)
- Marqueur
Unconjugated (3)- (2)
| Numéro de produit | Espèces | Système d'expression | Description du produit | Structure protéique | Pureté | Caractéristiques | Pré-commande/Commande |
|---|---|---|---|---|---|---|---|
HOT CHEK-ATF045 |  Human | HEK293 | Human TSLP R (Luc) HEK293 Reporter Cell |  |  Ajouter au panier | ||
HOT EP-129 | Human | - | TSLP [Biotinylated] : IL-7Rα & TSLP R Inhibitor Screening ELISA Kit | Ajouter au panier | |||
HOT ILR-H5255 | Human | HEK293 | Human IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag, low endotoxin (MALS verified) |  |  |  | Ajouter au panier |
ILR-H525x | Human | HEK293 | Human IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag |  | | | Ajouter au panier |
ILR-M5257 |  Mouse | HEK293 | Mouse IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag |  | | | Ajouter au panier |
Quantité totale5
- 1
IL-7 R alpha & TSLP RContexte de la molécule
TSLP is a pleiotropic cytokine originally characterized as a lymphocyte growth factor. Thymic stromal lymphopoietin (TSLP) is overexpressed in the airways of severe asthmatics and is an upstream cytokine that orchestrates inflammatory responses in asthma. Human TSLP exerts its biological activities by binding to a high-affinity heteromeric receptor complex composed of TSLPR and IL- 7 receptor and initiates signaling in cells co-expressing TSLPR and IL-7R.
IL-7 R alpha & TSLP RAlias de la molécule
IL7Ra,CD127,TSLP R,CRLF2,IL-XR,ILXR,p2RY8,CRLF2 fusion,TSLP receptor,TSLPR,CRL2,CRLF2Y,Cytokine receptor-like 2
Informations sur les médicaments cliniques
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Indication | Essai clinique |
|---|---|---|---|---|---|
| CYT-107 | CYT-107; CYT-99-007; rhIL-7 | Phase 2 Clinical | Revimmune Inc | Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Catheter-Related Infections; Coronavirus Disease 2019 (COVID-19); Hepatitis B, Chronic; Hepatitis C; HIV Infections; Kidney Neoplasms; Leukemia, Myelogenous, Chronic; Leukemia, Myeloid, Acute; Lymphopenia; Metastatic breast cancer; Multiple Myeloma; Mycobacterium Infections, Nontuberculous; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Sarcoma; Sarcoma, Kaposi; Sepsis; Shock, Septic; Skin Melanoma; T-Lymphocytopenia, Idiopathic CD4-Positive; Ureteral Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urologic Neoplasms | Details |
| Lusvertikimab | OSE-127; S-95011; Effi-7; OSE-217 | Phase 2 Clinical | Effimune | Colitis, Ulcerative; Sjogren's Syndrome | Details |
| Efineptakin alfa | TJ-107; GX-I7; NT-I7 | Phase 2 Clinical | Gannex Pharma Co Ltd | Astrocytoma; Breast Neoplasms; Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Coronavirus Disease 2019 (COVID-19); Esophageal Neoplasms; Glioblastoma; Glioma; Gliosarcoma; HIV Infections; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Leukoencephalopathy, Progressive Multifocal; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphopenia; Melanoma; Multiple Myeloma; Oropharyngeal Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Papillomavirus Infections; Plasmablastic Lymphoma; Prostatic Neoplasms, Castration-Resistant; Sarcoma, Kaposi; Small Cell Lung Carcinoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms | Details |
| ASP-9801 | ASP-9801 | Phase 1 Clinical | Astellas Pharma Inc | Neoplasm Metastasis; Neoplasms; Solid tumours | Details |
| PF-06342674 | RN-168; PF-6342674; PF-06342674; ZB-168 | Phase 1 Clinical | Pfizer Inc | Diabetes Mellitus, Type 1; Multiple Sclerosis | Details |
| CD19-IL7Ra CAR-T cells therapy (Chulalongkorn University) | CMD-63; CMD63 | Phase 1 Clinical | Chulalongkorn University | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma | Details |
| Loco-regional B7H3 IL-7Ra CAR T Cell therapy(Chulalongkorn University) | Phase 1 Clinical | Chulalongkorn University, King Chulalongkorn Memorial Hospital | Brain Neoplasms; Diffuse Intrinsic Pontine Glioma; Neoplasms; Solid tumours | Details | |
| MDK-703 | MDK-703 | Phase 1 Clinical | Medikine Inc | Solid tumours | Details |
- Informations sur la molécule
- Liste de produits
- Informations sur les médicaments cliniques
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