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IL-8

IL-8 Overview

English NameInterleukin-8Approved Drugs1
Drugs in Clinical Trials5Target SynonymIL8/NAP1 form VI，T-cell chemotactic factor，GCP/IL-8 protein III，IL8/NAP1 form II，GCP/IL-8 protein II，(Ala-IL-8)77，Emoctakin，IL8/NAP1 form IV，LYNAP，IL8/NAP1 form III，IL8/NAP1 form V，GCP/IL-8 protein I，Neutrophil-Activating Peptide 1，Interleukin 8，GCP-1，MDNCF，NAP-1，IL8，Beta Endothelial Cell-Derived Neutrophil Activating Peptide，Lung Giant Cell Carcinoma-Derived Chemotactic Protein，Lymphocyte Derived Neutrophil Activating Peptide，Alveolar Macrophage Chemotactic Factor I，Tumor Necrosis Factor-Induced Gene 1，Small Inducible Cytokine Subfamily B， Member 8，Beta-Thromboglobulin-Like Protein，GCP1，LECT，LUCT，NAP1，IL-8，Interleukin-8，AMCF-I，SCYB8，Neutrophil-Activating Protein 1，B-ENAP，3-10C，K60，TSG-1，C-X-C Motif Chemokine Ligand 8，Monocyte-Derived Neutrophil Chemotactic Factor，Monocyte-Derived Neutrophil-Activating Peptide，Granulocyte Chemotactic Protein 1，Chemokine (C-X-C Motif) Ligand 8，(Ser-IL-8)72，Neutrophil-activating factor，MDNCF-c，C-X-C motif chemokine 8，Lymphocyte-derived neutrophil-activating factor，Protein 3-10C，IL-8(1-77)，NAF，GCP/IL-8 protein VI，GCP/IL-8 protein IV，IL8/NAP1 form I，MONAP，MDNCF-b，GCP/IL-8 protein V，CXCL8
Highest Development StageApproved
English NameInterleukin-8
Target SynonymIL8/NAP1 form VI，T-cell chemotactic factor，GCP/IL-8 protein III，IL8/NAP1 form II，GCP/IL-8 protein II，(Ala-IL-8)77，Emoctakin，IL8/NAP1 form IV，LYNAP，IL8/NAP1 form III，IL8/NAP1 form V，GCP/IL-8 protein I，Neutrophil-Activating Peptide 1，Interleukin 8，GCP-1，MDNCF，NAP-1，IL8，Beta Endothelial Cell-Derived Neutrophil Activating Peptide，Lung Giant Cell Carcinoma-Derived Chemotactic Protein，Lymphocyte Derived Neutrophil Activating Peptide，Alveolar Macrophage Chemotactic Factor I，Tumor Necrosis Factor-Induced Gene 1，Small Inducible Cytokine Subfamily B， Member 8，Beta-Thromboglobulin-Like Protein，GCP1，LECT，LUCT，NAP1，IL-8，Interleukin-8，AMCF-I，SCYB8，Neutrophil-Activating Protein 1，B-ENAP，3-10C，K60，TSG-1，C-X-C Motif Chemokine Ligand 8，Monocyte-Derived Neutrophil Chemotactic Factor，Monocyte-Derived Neutrophil-Activating Peptide，Granulocyte Chemotactic Protein 1，Chemokine (C-X-C Motif) Ligand 8，(Ser-IL-8)72，Neutrophil-activating factor，MDNCF-c，C-X-C motif chemokine 8，Lymphocyte-derived neutrophil-activating factor，Protein 3-10C，IL-8(1-77)，NAF，GCP/IL-8 protein VI，GCP/IL-8 protein IV，IL8/NAP1 form I，MONAP，MDNCF-b，GCP/IL-8 protein V，CXCL8
Approved Drugs1
Drugs in Clinical Trials5
Highest Development StageApproved

IL-8 Product List

  • Product Category

    Protein (5)Kits (3)

  • Product Status

    Launched (8)

  • Species

    Human (7)Rhesus macaque (1)

  • Tag

    His Tag (2)Fc Tag (1)His Tag & Avi Tag (1)- (3)Tag Free (1)

  • Conjugate

    Unconjugated (4)Biotin-labeled (1)- (3)

Total: 8
  • 1

IL-8 Background

Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. There are many receptors on the surface membrane capable of binding IL-8, the most frequently studied types are the G protein-coupled serpentine receptors CXCR1 and CXCR2. Expression and affinity for IL-8 differs between the two receptors (CXCR1 > CXCR2). IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.

IL-8 Synonyms

CXCL8,GCP1,IL8,LECT,LUCT,LYNAP,MDNCF,MONAP,NAF,NAP-1
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