LTBR

LTBR Informations sur la molécule

Nom anglais	Tumor necrosis factor receptor superfamily member 3	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	1	Alias de la cible	Lymphotoxin-beta receptor，Tumor necrosis factor receptor type III，LTBR，Tumor necrosis factor receptor superfamily member 3，D12S370，TNFRSF3，TNFCR，TNFR3，TNFR Superfamily， Member 3，Lymphotoxin B Receptor，LT-BETA-R，TNF-R-III，TNFR2-RP，TNF-RIII，TNFR-III，TNFR-RP，Lymphotoxin beta Receptor，Tumor necrosis factor C receptor，Tumor Necrosis Factor Receptor 2-Related Protein，Lymphotoxin Beta Receptor (TNFR Superfamily， Member 3)
Phase de R&D la plus avancée	Phase 1 Clinical

Nom anglais	Tumor necrosis factor receptor superfamily member 3
Alias de la cible	Lymphotoxin-beta receptor，Tumor necrosis factor receptor type III，LTBR，Tumor necrosis factor receptor superfamily member 3，D12S370，TNFRSF3，TNFCR，TNFR3，TNFR Superfamily， Member 3，Lymphotoxin B Receptor，LT-BETA-R，TNF-R-III，TNFR2-RP，TNF-RIII，TNFR-III，TNFR-RP，Lymphotoxin beta Receptor，Tumor necrosis factor C receptor，Tumor Necrosis Factor Receptor 2-Related Protein，Lymphotoxin Beta Receptor (TNFR Superfamily， Member 3)
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	1
Phase de R&D la plus avancée	Phase 1 Clinical

LTBR Liste de produits

Attribut
Protein (5)
Bibliothèque de produits
En ligne (5)
Espèces
Human (3)Cynomolgus (1)Mouse (1)
Étiquette
His Tag & Avi Tag (2)Fc Tag (1)His Tag (2)
Marqueur
Biotin-labeled (1)Unconjugated (4)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT LTR-H5259	Human	HEK293	Human LTBR / TNFRSF3 Protein, Fc Tag (MALS verified)	Ajouter au panier
HOT LTR-H52E3	Human	HEK293	Unconjugated Human LTBR / TNFRSF3 Protein, His,Avitag™ (MALS verified)	Ajouter au panier
HOT LTR-H82E9	Human	HEK293	Biotinylated Human LTBR / TNFRSF3 Protein, His,Avitag™ (MALS verified)	Ajouter au panier
LTR-M52H3	Mouse	HEK293	Mouse LTBR / TNFRSF3 Protein, His Tag (MALS verified)	Ajouter au panier
LTR-C52H3	Cynomolgus	HEK293	Cynomolgus LTBR / TNFRSF3 Protein, His Tag	Ajouter au panier

Quantité totale5

LTBRContexte de la molécule

Lymphotoxin-beta receptor (LTBR) is also known as Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), Tumor necrosis factor receptor type III (TNF-RIII), which is a single-pass type I membrane protein containing four TNFR-Cys repeat regions. Except for interacting with HCV core protein, LTBR can not only associate with itself, but also can associate with TRAF3, TRAF4 and TRAF5. As the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT, LTBR promotes apoptosis via TRAF3 and TRAF5. Furthermore, LTBR may play a role in the development of lymphoid organs.