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Page d'accueilToutes les moléculesLY75
LY75
LY75 Informations sur la molécule
| Nom anglais | Lymphocyte antigen 75 | Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 1 | Alias de la cible | LY75，CD205，Lymphocyte Antigen 75，C-Type Lectin Domain Family 13 Member B，CLEC13B，DEC-205，CD205 Antigen，Gp200-MR6，Ly-75 |
| Phase de R&D la plus avancée | Phase 1 Clinical | ||
| Nom anglais | Lymphocyte antigen 75 |
| Alias de la cible | LY75，CD205，Lymphocyte Antigen 75，C-Type Lectin Domain Family 13 Member B，CLEC13B，DEC-205，CD205 Antigen，Gp200-MR6，Ly-75 |
| Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 1 |
| Phase de R&D la plus avancée | Phase 1 Clinical |
LY75 Liste de produits
- Attribut
Protein (2)
- Bibliothèque de produits
En ligne (2)
- Espèces
Mouse (1)Human (1)
- Étiquette
His Tag (2)
- Marqueur
Unconjugated (2)
| Numéro de produit | Espèces | Système d'expression | Description du produit | Structure protéique | Pureté | Caractéristiques | Pré-commande/Commande |
|---|---|---|---|---|---|---|---|
LY5-H52H3 |  Human | HEK293 | Human LY75 / CD205 Protein, His Tag |  |  |  Ajouter au panier | |
LY5-M52H5 |  Mouse | HEK293 | Mouse LY75 / CD205 Protein, His Tag (MALS verified) |  | | Ajouter au panier |
Quantité totale2
- 1
LY75Contexte de la molécule
lymphocyte antigen 75 (Ly 75, also known as CD205, CLEC13B, GP200-MR6 and DEC-205, is a type I transmembrane protein that is primarily expressed on dendritic cells and thymic epithelial cells. LY75 functions as an endocytic receptor for antigens. MEN1309/OBT076, the first antibody drug targeting CD205, has shown strong preclinical anti-tumor activity in lymphoma. After being verified as a single drug in vivo, the antibody-drug conjugate has a synergistic effect with the BCL2 inhibitor Venetoclax and the anti-cd20 monoclonal antibody rituximab.
LY75Alias de la molécule
LY75,CD205,DEC-205,CLEC13B,Lymphocyte antigen 75,gp200-MR6
Informations sur les médicaments cliniques
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Indication | Essai clinique |
|---|---|---|---|---|---|
| Oberotatug ravtansine | OBT-076; MEN1309/OBT076; MEN-1309 | Phase 1 Clinical | Menarini, Oxford Biotherapeutics Ltd | Carcinoma, Adenoid Cystic; Head and Neck Neoplasms; Lymphoma, Non-Hodgkin; Solid tumours | Details |
- Informations sur la molécule
- Liste de produits
- Informations sur les médicaments cliniques
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