MASP3 Informations sur la molécule
Molecule Name
Mannan-binding lectin serine protease 1
Alias de la molécule
MASP3, MASP1, CRARF1, RaRF
Drug Development Progress
Nombre de médicaments cliniques0
Nombre de médicaments commercialisés0
Phase de R&D la plus avancée
Alias de la cible
Complement-activating component of Ra-reactive factor，Mannose-binding lectin-associated serine protease 1 (MASP-1)，Mannose-binding protein-associated serine protease，Ra-reactive factor serine protease p100 (RaRF)，Serine protease 5，MASP1，CRARF，PRSS5，Complement factor MASP-3
Contexte de la molécule
MASP3 is a member of the MASP family. The MASP family proteins were first
discovered as complexes with mannose-binding lectin (MBL) and therefore named MBL-associated
serine proteases, but later, they were found to interact with ficolins, and later still, collectin-10
and collectin-11. As well as proteolytic enzymes (MASP-1, MASP-2, MASP-3), the group includes
non-enzymatic factors (MAp19, MAp44). In this review, the association-specific factors of the lectin
pathway with haematologic malignancies and related infections are discussed.
MASP3 Liste de produits
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