MIS RII

MIS RII Informations sur la molécule

Nom anglais	Anti-Mullerian hormone receptor II	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0	Alias de la cible	Anti-Mullerian Hormone Receptor， Type II，AMHR2，MRII，AMH Type II Receptor，MISRII，Muellerian Inhibiting Substance Type II Receptor，MIS Type II Receptor，Anti-Muellerian hormone type-2 receptor，EC:2.7.11.30，Mullerian Inhibiting Substance Type II Receptor，MISR2，AMHR，Anti-Muellerian Hormone Type-2 Receptor，Anti-Mullerian Hormone Receptor Type 2，EC 2.7.11.30，Anti-Muellerian Hormone Type II Receptor，Anti-Mullerian Hormone Receptor Type II
Phase de R&D la plus avancée	Preclinical

Nom anglais	Anti-Mullerian hormone receptor II
Alias de la cible	Anti-Mullerian Hormone Receptor， Type II，AMHR2，MRII，AMH Type II Receptor，MISRII，Muellerian Inhibiting Substance Type II Receptor，MIS Type II Receptor，Anti-Muellerian hormone type-2 receptor，EC:2.7.11.30，Mullerian Inhibiting Substance Type II Receptor，MISR2，AMHR，Anti-Muellerian Hormone Type-2 Receptor，Anti-Mullerian Hormone Receptor Type 2，EC 2.7.11.30，Anti-Muellerian Hormone Type II Receptor，Anti-Mullerian Hormone Receptor Type II
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0
Phase de R&D la plus avancée	Preclinical

MIS RII Liste de produits

Attribut
Protein (7)
Bibliothèque de produits
En ligne (7)
Espèces
Human (5)Cynomolgus (1)Mouse (1)
Étiquette
Fc Tag (1)His Tag (3)His Tag & Avi Tag (1)Mouse IgG Fc Tag (1)Llama IgG Fc Tag (1)
Marqueur
Unconjugated (6)Biotin-labeled (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT MII-H5253	Human	HEK293	Human MIS RII Protein, Mouse IgG2a Fc Tag	Ajouter au panier
HOT MII-H5258	Human	HEK293	Human MIS RII Protein, Fc Tag	Ajouter au panier
HOT MII-H52H6	Human	HEK293	Human MIS RII Protein, His Tag	Ajouter au panier
HOT MII-M52H6	Mouse	HEK293	Mouse MIS RII Protein, His Tag	Ajouter au panier
MII-H5254	Human	HEK293	Human MIS RII Protein, Llama IgG2b Fc Tag, low endotoxin	Ajouter au panier
MII-H82E3	Human	HEK293	Biotinylated Human MIS RII Protein, His,Avitag™	Ajouter au panier
MII-C52H5	Cynomolgus	HEK293	Cynomolgus MIS RII Protein, His Tag	Ajouter au panier

Quantité totale7

MIS RIIContexte de la molécule

MIS RII (Mullerian inhibiting substance type II receptor), also known as AMHRII (anti-Mullerian hormone type II receptor), is a serine/threonine receptor with a single transmembrane domain that belongs to the family of type II receptors of the TGF-beta superfamily. Mutations in MIS RII result in persistent Mullerian duct syndrome (PMDS), persistent Müllerian duct syndrome (PMDS) is a sex-limited disorder in which males develop portions of the female reproductive tract. Anti-Müllerian hormone (AMH) and its receptor (AMHR2) induce the regression of the Müllerian ducts in male embryos, but the mechanism by which the Amhr2 gene is specifically activated is not fully understood.

MIS RIIAlias de la molécule

MIS RII,MRII,AMHR2,AMHR,MISR2,AMH type II receptor

Avis sur les produits

K***n2025-04-29
0Mettre un like
Human MIS RII Protein, Fc Tag
We purchased this protein and validated its binding to its natural ligand, MIS. We saw great binding between the hMISRII-hFc and MIS ligand, which was exactly what we expected. Additionally, this protein passed our QC requirements for purity on SDS-PAGE and SEC. This was purchased along with several other MISRII products from other companies and this was the only material that bound MIS with expected affinity. As such, we plan to use this protein for our downstream applications.