MMP-3

MMP-3 Informations sur la molécule

Nom anglais	Matrix metalloproteinase 3	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0	Alias de la cible	CHDS6，STR1，STMY，Matrix Metalloproteinase 3，Matrix metalloproteinase-3，MMP-3，SL-1，STMY1，MMP3，Matrix Metalloproteinase 3 (Stromelysin 1， Progelatinase)，Transin-1，Proteoglycanase，Stromelysin-1，Stromelysin 1，EC 3.4.24.17，EC:3.4.24.17，EC 3.4.24，Matrix Metallopeptidase 3
Phase de R&D la plus avancée	Preclinical

Nom anglais	Matrix metalloproteinase 3
Alias de la cible	CHDS6，STR1，STMY，Matrix Metalloproteinase 3，Matrix metalloproteinase-3，MMP-3，SL-1，STMY1，MMP3，Matrix Metalloproteinase 3 (Stromelysin 1， Progelatinase)，Transin-1，Proteoglycanase，Stromelysin-1，Stromelysin 1，EC 3.4.24.17，EC:3.4.24.17，EC 3.4.24，Matrix Metallopeptidase 3
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0
Phase de R&D la plus avancée	Preclinical

MMP-3 Liste de produits

Attribut
Protein (1)
Bibliothèque de produits
En ligne (1)
Espèces
Human (1)
Étiquette
His Tag (1)
Marqueur
Unconjugated (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
MM3-H52H3	Human	HEK293	Human MMP-3 Protein, His Tag (Pro-form, MALS verified)				Ajouter au panier

Quantité totale1

MMP-3Contexte de la molécule

Matrix metalloproteinase 3 (MMP-3), also known as stromelysin 1 and progelatinase, is encoded by the MMP3 gene. The expression of MMP3 is mainly regulated at the transcriptional level, where gene promoters respond to a variety of stimuli including growth factors, cytokines, carcinogens and proto-oncogene products. MMP-3 degrade II, III, IV, IX and X collagen, proteoglycan, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7 and MMP-9, so MMP-3 plays a key role in connective tissue remodeling. This enzyme is involved in wound repair, atherosclerotic progression, and tumor initiation. Studies of MMP-3 wild type and gene knockout in mice have shown that MMP-3 increases the permeability of the blood-brain barrier after traumatic injury. Nuclear MMP-3 works as a transcription factor and protease.