MMP-8 Informations sur la molécule
Molecule Name
Matrix metalloproteinase 8
Alias de la molécule
CLG1 Protein, HNC Protein, MMP-8 Protein, PMNL-CL Protein,
Drug Development Progress
Nombre de médicaments cliniques0
Nombre de médicaments commercialisés0
Phase de R&D la plus avancéePreclinical
Alias de la cible
EC 3.4.24，Matrix metalloproteinase-8，MMP-8，MMP8，Matrix Metallopeptidase 8，Matrix Metalloproteinase 8 (Neutrophil Collagenase)，PMNL-CL，CLG1，PMN Leukocyte Collagenase，Neutrophil Collagenase，EC 3.4.24.34，HNC，Matrix Metalloproteinase 8，EC:3.4.24.34，PMNL Collagenase，Collagenase 2
Contexte de la molécule
Matrix metalloproteinase-8（MMP-8）also known as neutrophil collagenase and CLG1，is a member of matrix metalloproteinases (MMPs) family，which degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes as well as pathological processes. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 in the tumor may have a protective effect against lymph node metastasis.
MMP-8 Liste de produits
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