Monoamine oxidase B Informations sur la molécule
Molecule Name
Monoamine oxidase B
Alias de la molécule
MAOB, MAO-B,Monoamine Oxidase B,Monoamine oxidase type B
Drug Development Progress
Nombre de médicaments cliniques13
Nombre de médicaments commercialisés3
Phase de R&D la plus avancéeApproved
Alias de la cible
EC:1.4.3.4，EC 1.4.3，MAOB，Amine oxidase [flavin-containing] B，Monoamine Oxidase B，Monoamine Oxidase Type B，MAO-B，Adrenalin Oxidase，Tyramine Oxidase，MAO， Platelet，MAO， Brain，EC 1.4.3.4
Contexte de la molécule
Monoamine Oxidase Type B (MAOB) is an enzyme located in the outer mitochondrial membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the breakdown of dopamine in the brain. MAOB inhibitors, that reduces dopamine turnover, are in clinical use for the treatment of Parkinson's disease (PD).
Monoamine oxidase B Liste de produits
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Coopération sous licence
| Nom du projet | Type de médicament | Domain thérapeutique | Indication | Phase | Zone de droits |
|---|---|---|---|---|---|
| Reversible MAOB Inhibitor | Small molecule | Neurological disease | Parkinson's disease | Phase I | Global |
- Nom du projet
- Reversible MAOB Inhibitor
- Type de médicament
- Small molecule
- Domain thérapeutique
- Neurological disease
- Indication
- Parkinson's disease
- Phase
- Phase I
- Zone de droits
- Global