NGFR

NGFR Informations sur la molécule

Nom anglais	Low affinity neurotrophin receptor p75NTR	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	3	Alias de la cible	Gp80-LNGFR，P75NTR，CD271 Antigen，Low-Affinity Nerve Growth Factor Receptor，Tumor Necrosis Factor Receptor Superfamily Member 16，Low Affinity Nerve Growth Factor Receptor，Low Affinity Neurotrophin Receptor P75NTR，Nerve Growth Factor Receptor (TNFR Superfamily， Member 16)，TNFR Superfamily， Member 16，Nerve Growth Factor Receptor，P75 ICD，P75(NTR)，TNFRSF16，CD271
Phase de R&D la plus avancée	Phase 2 Clinical

Nom anglais	Low affinity neurotrophin receptor p75NTR
Alias de la cible	Gp80-LNGFR，P75NTR，CD271 Antigen，Low-Affinity Nerve Growth Factor Receptor，Tumor Necrosis Factor Receptor Superfamily Member 16，Low Affinity Nerve Growth Factor Receptor，Low Affinity Neurotrophin Receptor P75NTR，Nerve Growth Factor Receptor (TNFR Superfamily， Member 16)，TNFR Superfamily， Member 16，Nerve Growth Factor Receptor，P75 ICD，P75(NTR)，TNFRSF16，CD271
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	3
Phase de R&D la plus avancée	Phase 2 Clinical

NGFR Liste de produits

Attribut
Protein (1)Cell (1)
Bibliothèque de produits
En ligne (2)
Espèces
Human (2)
Étiquette
Fc Tag (1)- (1)
Marqueur
Unconjugated (1)- (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
CHEK-ATP157	Human	HEK293	HEK293/Human NGFR Stable Cell Line				Ajouter au panier
NGR-H5254	Human	HEK293	Human NGFR / TNFRSF16 Protein, Fc Tag (MALS & BLI verified)				Ajouter au panier

Quantité totale2

NGFRContexte de la molécule

The p75 neurotrophin receptor (p75NTR) was originally identified as a low-affinity receptor for neurotrophins(NGF R).p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3, Brain-derived neurotrophic factor, and Neurotrophin-4. All neurotrophins bind to p75NTR. This also includes the immature pro-neurotrophin forms. Neurotrophic factor receptors, including p75NTR, are responsible for ensuring a proper density to target ratio of developing neurons, refining broader maps in development into precise connections. p75NTR is involved in pathways that promote neuronal survival and neuronal death.

NGFRAlias de la molécule

tumor necrosis factor receptor superfamily member 16; CD271; Gp80-LNGFR; member 16 nerve growth factor receptor; p75 ICD; p75 NTR

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
LM11A-31	LM11A-31; LM11A-31-BHS	Phase 2 Clinical	Pharmatrophix Inc	Alzheimer Disease; Supranuclear Palsy, Progressive	Details
Recombinant human nerve growth factor (Xintrum Pharmacouticals)	rh-NGF; ZX1305; ZX-1305; ZX1305E; ZX-1305-E	Phase 2 Clinical	Jiangsu Zhongxin Pharmaceutical Co Ltd	Glaucoma, Open-Angle; Keratitis; Optic Nerve Injuries	Details
Recombinant Human Nerve Growth Factor (Kerun Biopharmaceutical)		Phase 1 Clinical	Chongqing Kerun Biologic Pharmaceutical Development Co Ltd	Keratitis; Xerophthalmia	Details