NKp44 Overview
Molecule Name
Natural cytotoxicity triggering receptor 2
Synonyms
Natural cytotoxicity triggering receptor 2,NKp44,NCR2,CD336,LY95
Drug Development Progress
Drugs in Clinical Trials0
Approved Drugs0
Highest Development Stage
Target Synonym
Lymphocyte antigen 95 homolog，NK cell-activating receptor，Natural killer cell p44-related protein，NK-p44，NKp44，CD336，LY95
Background
NKp44, a member of Natural Cytotoxicity Receptors (NCRs), is an activating receptor playing a crucial role in most functions exerted by activated NK cells and also by other NKp44+ immune cells. Membrane-associated PCNA is a ligand for the NKp44 (NCR2) innate immune receptorMembrane-associated PCNA is a ligand for the NKp44 (NCR2) innate immune receptor. NKp44 / NCR2 / CD336 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
NKp44 Product List
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