NRG1 Beta 1

NRG1 Beta 1 Informations sur la molécule

Nom anglais	Neuregulin-1	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0	Alias de la cible	Sensory and motor neuron-derived factor，Pro-neuregulin-1， membrane-bound isoform，Glial growth factor，Neuregulin-1，Acetylcholine receptor-inducing activity，Pro-NRG1，ARIA，Breast cancer cell differentiation factor p45，Neu differentiation factor，Heregulin，HRG
Phase de R&D la plus avancée	Preclinical

Nom anglais	Neuregulin-1
Alias de la cible	Sensory and motor neuron-derived factor，Pro-neuregulin-1， membrane-bound isoform，Glial growth factor，Neuregulin-1，Acetylcholine receptor-inducing activity，Pro-NRG1，ARIA，Breast cancer cell differentiation factor p45，Neu differentiation factor，Heregulin，HRG
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0
Phase de R&D la plus avancée	Preclinical

NRG1 Beta 1 Liste de produits

Attribut
Protein (2)
Bibliothèque de produits
En ligne (2)
Espèces
Human (2)
Étiquette
Fc Tag (1)His Tag (1)
Marqueur
Unconjugated (2)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
NR1-H5246	Human	HEK293	Human NRG1 Beta 1 Protein, His Tag, premium grade				Ajouter au panier
NR1-H5268	Human	HEK293	Human NRG1 Beta 1 Protein, Fc Tag, premium grade				Ajouter au panier

Quantité totale2

NRG1 Beta 1Contexte de la molécule

NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specific and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains; and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through their displayed interaction with ERBB receptors, NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells.