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Page d'accueilToutes les moléculesORF8
ORF8
ORF8 Liste de produits
- Attribut
Protein (1)
- Bibliothèque de produits
En ligne (1)
- Espèces
SARS-CoV-2 (1)
- Étiquette
His Tag (1)
- Marqueur
Unconjugated (1)
| Numéro de produit | Espèces | Système d'expression | Description du produit | Structure protéique | Pureté | Caractéristiques | Pré-commande/Commande |
|---|---|---|---|---|---|---|---|
OR8-C52H1 | SARS-CoV-2 | HEK293 | SARS-CoV-2 ORF8 Protein, His Tag (MALS verified) |  |  |  Ajouter au panier |
Quantité totale1
- 1
ORF8Contexte de la molécule
The viral protein encoded by open reading frame 8 (ORF8) of SARS-CoV-2, which shares the least homology with SARS-CoV among all viral proteins, directly interacts with MHC-Ι molecules and mediates their down-regulation. In ORF8-expressing cells, MHC-Ι molecules are selectively targeted for lysosomal degradation via autophagy. Thus, SARS-CoV-2–infected cells are much less sensitive to lysis by cytotoxic T lymphocytes.
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