OSMR

OSMR

OSMR Overview

Molecule Name
Oncostatin-M-specific receptor subunit beta
Synonyms
Oncostatin-M-specific receptor subunit beta,Interleukin-31 receptor subunit beta,IL-31 receptor subunit beta,IL-31R subunit beta,IL-31R-beta,IL-31RB,OSMR,OSMRB
Drug Development Progress
Drugs in Clinical Trials1
Approved Drugs0
Highest Development StagePhase 2 Clinical
Target Synonym
IL-31R-beta,IL-31RB,Interleukin-31 receptor subunit beta,IL-31 receptor subunit beta,IL-31R subunit beta
Background
Oncostatin-M-specific receptor subunit beta (OSMRβ), also known as Interleukin-31 receptor subunit beta (IL-31RB), is the beta subunit of the type II OSM receptor, which is a heterodimer of gp130 and OSMRβ. OSMRβ associates with the low-affinity OSM·gp130 complex to form a high-affinity heterodimeric receptor that is capable of transducing OSM-specific signaling events.

OSMR Product List

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Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
VixarelimabKPL-716; BIIB-069; RG-6536; RO-7622888Phase 2 ClinicalBiogen Inc
Chronic Urticaria; Colitis, Ulcerative; Lichen Planus; Neurodermatitis; Plaque psoriasis; Prurigo Nodularis; Pruritus
Details