P-Selectin

P-Selectin Informations sur la molécule

Nom anglais	P-selectin	Nombre de médicaments commercialisés	1
Nombre de médicaments cliniques	1	Alias de la cible	Platelet Activation Dependent Granule-External Membrane Protein，Granule Membrane Protein 140kDa，PADGEM，GRMP，Selectin P (Granule Membrane Protein 140kD， Antigen CD62)，Platelet Alpha-Granule Membrane Protein，Granulocyte Membrane Protein，CD62P Antigen，Antigen CD62，P-Selectin，GMP140，CD62P，CD62，PSEL，LECAM3，CD62 antigen-like family member P，GMRP，GMP-140，Granule membrane protein 140，SELP，Selectin P，Selectin P (Granule Membrane Protein 140kDa， Antigen CD62)，Leukocyte-Endothelial Cell Adhesion Molecule 3
Phase de R&D la plus avancée	Approved

Nom anglais	P-selectin
Alias de la cible	Platelet Activation Dependent Granule-External Membrane Protein，Granule Membrane Protein 140kDa，PADGEM，GRMP，Selectin P (Granule Membrane Protein 140kD， Antigen CD62)，Platelet Alpha-Granule Membrane Protein，Granulocyte Membrane Protein，CD62P Antigen，Antigen CD62，P-Selectin，GMP140，CD62P，CD62，PSEL，LECAM3，CD62 antigen-like family member P，GMRP，GMP-140，Granule membrane protein 140，SELP，Selectin P，Selectin P (Granule Membrane Protein 140kDa， Antigen CD62)，Leukocyte-Endothelial Cell Adhesion Molecule 3
Nombre de médicaments commercialisés	1
Nombre de médicaments cliniques	1
Phase de R&D la plus avancée	Approved

P-Selectin Liste de produits

Attribut
Protein (2)
Bibliothèque de produits
En ligne (2)
Espèces
Human (2)
Étiquette
His Tag (1)Fc Tag (1)
Marqueur
Unconjugated (2)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
SEP-H5255	Human	HEK293	Human P-Selectin / CD62P Protein, Fc Tag				Ajouter au panier
SEP-H52E4	Human	HEK293	Human P-Selectin / CD62P Protein, His Tag				Ajouter au panier

Quantité totale2

P-SelectinContexte de la molécule

P-selectin (SELP) is also known as CD62 antigen-like family member P, granule membrane protein 140 (GMP-140), leukocyte-endothelial cell adhesion molecule 3 (LECAM3) and platelet activation dependent granule-external membrane protein (PADGEM). SELP functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets. In unactivated endothelial cells, it is stored in granules called Weibel-Palade bodies. In unactivated platelets SELP is stored in α-granules. The primary ligand for SELP is P-selectin glycoprotein ligand-1 (PSGL-1) which is expressed on almost all leukocytes, although P-selectin also binds to heparan sulfate and fucoidan. Furthermore, SELP has a functional role in metastasis of tumor similar to E-selectin, which can help cancer cells invade into bloodstream for metastasis and provided locally with multiple growth factors respectively.

P-SelectinAlias de la molécule

P-Selectin,CD62P,SELP,GMP-140

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
Inclacumab	DSM-ACC-2641; RO 4905417; LC1004-002; DSM ACC2641; RG-1512; LC-1004-002; R-1512; PF-07940370; RO-4905417	Phase 3 Clinical	F. Hoffmann-La Roche Ltd, Genmab A/S	Anemia, Sickle Cell; Graft Occlusion, Vascular; Myocardial Infarction; Pain; Peripheral Arterial Disease	Details

Informations sur les médicaments commercialisés

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Plus ancien nom de marque	Pays d'approbation le plus ancien	Indication la plus ancienne	Société d'approbation la plus ancienne	Date d'approbation la plus ancienne	Indication	Essai clinique
Crizanlizumab	Sel-G-1; SEG-101; SEG101; Sel-G1	Approved	Selexys Pharmaceuticals Corp	Adakveo, Ryverna	United States	Anemia, Sickle Cell	Novartis Pharmaceuticals Corp	2019-11-15	Anemia, Sickle Cell; Coronavirus Disease 2019 (COVID-19); Leukoencephalopathies; Priapism; Primary Myelofibrosis	Details

Avis sur les produits

V***u2023-07-13
2Mettre un like
Human P-Selectin / CD62P Protein, His Tag
AcroBio is our go to vendor, for our growing biotechnology start up. The customer service at acro bio is excellent, products have never failed in our labs. The specific product we got is the Human P-selectin/CD62P Protein His Tag which our lab has gotten multiple times and has not failed us. Thank you AcroBio for your amazing services, we appreciate you!