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PADI2

PADI2 Liste de produits

  • Attribut

    Protein (3)

  • Bibliothèque de produits

    En ligne (3)

  • Espèces

    Human (1)Mouse (1)Cynomolgus (1)

  • Étiquette

    His Tag (3)

  • Marqueur

    Unconjugated (3)

Numéro de produitEspècesSystème d'expressionDescription du produitStructure protéiquePuretéCaractéristiquesPré-commande/Commande
HOT
PA2-C5545
Cynomolgus
InsectCells
Cynomolgus PADI2 Protein, His Tag (MALS verified)
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PA2-H5543
Human
InsectCells
Human PADI2 Protein, His Tag, low Endotoxin (InsectCells) (active enzyme)
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PA2-M5544
Mouse
InsectCells
Mouse PADI2 Protein, His Tag (MALS verified)
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Quantité totale3
  • 1

PADI2Contexte de la molécule

Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer. This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.
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