Platelet glycoprotein V

Platelet glycoprotein V Liste de produits

Attribut
Protein (1)
Bibliothèque de produits
En ligne (1)
Espèces
Human (1)
Étiquette
His Tag & Avi Tag (1)
Marqueur
Biotin-labeled (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
PLV-H82E3	Human	HEK293	Biotinylated Human Platelet glycoprotein V Protein, His,Avitag™ (MALS verified)				Ajouter au panier

Quantité totale1

Platelet glycoprotein VContexte de la molécule

Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010]

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
LHF-535	LHF-535; LHF-535-SDD	Phase 1 Clinical	Kineta Inc		Details
SAR-440894	SAR-440894	Phase 1 Clinical	National Institute Of Allergy And Infectious Diseases (Niaid)	Chikungunya Fever	Details