Plectin

Plectin

Plectin Overview

Molecule Name
Plectin
Synonyms
Plectin,PLTN,PCN,HD1,Hemidesmosomal protein 1,PLEC1
Drug Development Progress
Drugs in Clinical Trials1
Approved Drugs0
Highest Development StagePhase 2 Clinical
Target Synonym
PLTN,Hemidesmosomal protein 1
Background
Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity.

Plectin Product List

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Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
IbentatugZB-131Phase 2 ClinicalZielbio Inc
Biliary Tract Neoplasms; Carcinoma, Pancreatic Ductal; Cystadenocarcinoma, Serous; Ovarian Neoplasms; Solid tumours
Details