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Page d'accueilToutes les moléculesPNU-159682
PNU-159682
PNU-159682 Liste de produits
- Attribut
Antibody (3)
- Bibliothèque de produits
En ligne (3)
- Espèces
Rabbit (3)
- Étiquette
- (3)
- Marqueur
Unconjugated (3)
| Numéro de produit | Espèces | Système d'expression | Description du produit | Structure protéique | Pureté | Caractéristiques | Pré-commande/Commande |
|---|---|---|---|---|---|---|---|
PNU-MY2370 |  Rabbit | HEK293 | Monoclonal Anti-PNU-159682 Antibody, Rabbit IgG (P1D10) |  |  Ajouter au panier | ||
PNU-MY2371 | Rabbit | HEK293 | Monoclonal Anti-PNU-159682 Antibody, Rabbit IgG (P1C01) | | Ajouter au panier | ||
PNU-MY2372 | Rabbit | HEK293 | Monoclonal Anti-PNU-159682 Antibody, Rabbit IgG (M1E11) | | Ajouter au panier |
Quantité totale3
- 1
PNU-159682Contexte de la molécule
PNU-159682 is a topoisomerase II inhibitor serving as a payload for antibody-drug conjugates (ADCs). Its mechanism of action involves stabilizing the complex formed by topoisomerase II and DNA, blocking DNA repair and replication processes, and thereby inducing cancer cell apoptosis. Some ADCs containing PNU-159682 have entered the preclinical research stage, showing targeted killing activity in solid tumor models, with particularly significant effects on tumors with high topoisomerase II expression.
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