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Page d'accueilToutes les moléculesProlactin R
Prolactin R
Prolactin R Informations sur la molécule
| Nom anglais | Prolactin receptor | Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 2 | Alias de la cible | PRL-R，PRLR，Prolactin Receptor，Secreted Prolactin Binding Protein，HPRL Receptor，RI-PRLR，HPRLrI，HPRL，MFAB，Receptors， Prolactin |
| Phase de R&D la plus avancée | Phase 3 Clinical | ||
| Nom anglais | Prolactin receptor |
| Alias de la cible | PRL-R，PRLR，Prolactin Receptor，Secreted Prolactin Binding Protein，HPRL Receptor，RI-PRLR，HPRLrI，HPRL，MFAB，Receptors， Prolactin |
| Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 2 |
| Phase de R&D la plus avancée | Phase 3 Clinical |
Prolactin R Liste de produits
- Attribut
Protein (7)
- Bibliothèque de produits
En ligne (7)
- Espèces
Human (4)Cynomolgus (1)Rat (1)Mouse (1)
- Étiquette
Fc Tag (1)His Tag (5)His Tag & Avi Tag (1)
- Marqueur
Unconjugated (6)Biotin-labeled (1)
| Numéro de produit | Espèces | Système d'expression | Description du produit | Structure protéique | Pureté | Caractéristiques | Pré-commande/Commande |
|---|---|---|---|---|---|---|---|
 Human | HEK293 | Human Prolactin R / PRLR Protein, Fc Tag |  |  |  |  Ajouter au panier | |
| Human | HEK293 | Human Prolactin R / PRLR Protein, His Tag&Tag Free, low endotoxin (MALS verified) | | | Ajouter au panier | ||
| Human | HEK293 | Human Prolactin R / PRLR Protein, His Tag |  | | | Ajouter au panier | |
| Human | HEK293 | Biotinylated Human Prolactin R / PRLR Protein, His,Avitag™ (MALS verified) |  | | | Ajouter au panier | |
 Mouse | HEK293 | Mouse Prolactin R / PRLR Protein, His Tag (MALS & SPR verified) |  | |  | Ajouter au panier | |
 Cynomolgus | HEK293 | Cynomolgus Prolactin R Protein, His Tag (MALS verified) |  | | | Ajouter au panier | |
 Rat | HEK293 | Rat Prolactin R / PRLR Protein, His Tag (MALS & SPR verified) |  | | | Ajouter au panier |
Quantité totale7
- 1
Prolactin RContexte de la molécule
As a transmembrane receptor, the prolactin receptor (PRL-R) interacts with prolactin. In addition, the PRL-R also binds and is activated by growth hormone (GH) and human placental lactogen (hPL). Preclinical investigations, epidemiological studies and analyses of tissue specimens from patients strongly support the contribution of prolactin receptor (PRLR) signaling to breast and prostate tumorigenesis and cancer progression. Moreover, The PRLR has been found to be essential for lobuloalveolar maturation of the mammary glands during pregnancy, as evidenced by the fact that PRLR knockout mice show severely impaired development of lobuloalveolar structures.
Prolactin RAlias de la molécule
Prolactin R,PRLR,PRL-R
Informations sur les médicaments cliniques
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Indication | Essai clinique |
|---|---|---|---|---|---|
| BAY-1158061 | BAY-1158061; HMI-115 | Phase 3 Clinical | Bayer AG | Alopecia; Endometriosis; Pain | Details |
| ABS-201 | ABS-201 | Phase 2 Clinical | Absci Corp | Alopecia; Skin Diseases | Details |
- Informations sur la molécule
- Liste de produits
- Informations sur les médicaments cliniques
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