Properdin

Properdin Informations sur la molécule

Nom anglais	Properdin	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	2	Alias de la cible	Complement factor P，CFP
Phase de R&D la plus avancée	Phase 2 Clinical

Nom anglais	Properdin
Alias de la cible	Complement factor P，CFP
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	2
Phase de R&D la plus avancée	Phase 2 Clinical

Properdin Liste de produits

Attribut
Protein (3)
Bibliothèque de produits
En ligne (3)
Espèces
Human (1)Mouse (1)Rhesus macaque (1)
Étiquette
His Tag (3)
Marqueur
Unconjugated (3)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT PRN-H52H3	Human	HEK293	Human Properdin Protein, His Tag	Ajouter au panier
PRN-M52H5	Mouse	HEK293	Mouse Properdin Protein, His Tag	Ajouter au panier
PRN-R52H6	Rhesus macaque	HEK293	Rhesus macaque Properdin Protein, His Tag	Ajouter au panier

Quantité totale3

ProperdinContexte de la molécule

Properdin is also known as Complement factor P, CFP, PFC, a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin is produced by many different leukocyte subsets and circulates as cyclic oligomers of monomeric subunits. Properdin on platelet/granulocyte aggregates(PGA) formation are tightly regulated by Factor H, properdin enhances PGA formation via increased production of C5a, and that inhibition of properdin function has therapeutic potential to limit thromboinflammation in diseases characterized by increased PGA formation.

ProperdinAlias de la molécule

Properdin,Complement factor P,CFP,PFC

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
Tarperprumig	ALXN-1820	Phase 2 Clinical	Alexion Pharmaceuticals Inc	Anemia, Sickle Cell; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	Details
NM-5072	NM5072; NM-5072	Phase 1 Clinical	NovelMed Therapeutics Inc	Atypical Hemolytic Uremic Syndrome; Eye Diseases; Hemoglobinuria, Paroxysmal	Details