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Page d'accueilToutes les moléculesPVRIG
PVRIG
PVRIG Informations sur la molécule
| Nom anglais | Transmembrane protein PVRIG | Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 7 | Alias de la cible | PVRIG，PVR Related Immunoglobulin Domain Containing，CD112 Receptor，Poliovirus Receptor-Related Immunoglobulin Domain-Containing Protein，Poliovirus Receptor Related Immunoglobulin Domain Containing，Nectin-2 Receptor，C7orf15，CD112R，Transmembrane Protein PVRIG，MGC2463 |
| Phase de R&D la plus avancée | Phase 2 Clinical | ||
| Nom anglais | Transmembrane protein PVRIG |
| Alias de la cible | PVRIG，PVR Related Immunoglobulin Domain Containing，CD112 Receptor，Poliovirus Receptor-Related Immunoglobulin Domain-Containing Protein，Poliovirus Receptor Related Immunoglobulin Domain Containing，Nectin-2 Receptor，C7orf15，CD112R，Transmembrane Protein PVRIG，MGC2463 |
| Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 7 |
| Phase de R&D la plus avancée | Phase 2 Clinical |
PVRIG Liste de produits
- Attribut
Protein (11)
- Bibliothèque de produits
En ligne (11)
- Espèces
Human (5)Mouse (4)Cynomolgus (2)
- Étiquette
His Tag (4)Fc Tag (3)His Tag & Avi Tag (2)Mouse IgG Fc Tag (1)Fc Tag & Avi Tag (1)
- Marqueur
Unconjugated (8)Biotin-labeled (3)
| Numéro de produit | Espèces | Système d'expression | Description du produit | Structure protéique | Pureté | Caractéristiques | Pré-commande/Commande |
|---|---|---|---|---|---|---|---|
HOT PVG-H5257 |  Human | HEK293 | Human PVRIG Protein, Fc Tag, low endotoxin (MALS verified) |  |  |  |  Ajouter au panier |
HOT PVG-H5259 | Human | HEK293 | Human PVRIG Protein, Mouse IgG2a Fc Tag (MALS verified) |  | | | Ajouter au panier |
HOT PVG-H52H4 | Human | HEK293 | Human PVRIG Protein, His Tag |  | | | Ajouter au panier |
HOT PVG-H82E3 | Human | HEK293 | Biotinylated Human PVRIG Protein, His,Avitag™ |  | | | Ajouter au panier |
| Human | HEK293 | Human PVRIG Protein, His Tag (MALS verified) |  | | | Ajouter au panier | |
 Mouse | HEK293 | Mouse PVRIG Protein, Fc Tag (MALS verified) |  | | Ajouter au panier | ||
| Mouse | HEK293 | Mouse PVRIG Protein, His Tag (MALS verified) |  | | Ajouter au panier | ||
| Mouse | HEK293 | Biotinylated Mouse PVRIG Protein, His,Avitag™ |  | | Ajouter au panier | ||
| Mouse | HEK293 | Biotinylated Mouse PVRIG Protein, Fc,Avitag™ (MALS verified) |  | | Ajouter au panier | ||
 Cynomolgus | HEK293 | Cynomolgus PVRIG Protein, Fc Tag (MALS verified) |  | | | Ajouter au panier |
Quantité totale11
- 1
- 2
PVRIGContexte de la molécule
Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
PVRIGAlias de la molécule
C7orf15,C7orf15MGC138295,CD112R,MGC104322,MGC138297,MGC2463,PVRIG,CD112 receptor
Plateforme de commerce de projets d'anticorps
| Nom du projet | Phase du projet | Type de molécule | Source de molécule | Domain thérapeutique | Indication |
|---|---|---|---|---|---|
| TIGIT&PVRIG BsAb - 01 | PCC | Monoclonal | Humanized Mouse | Solid Tumor | Solid tumor |
Informations sur les médicaments cliniques
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Indication | Essai clinique |
|---|---|---|---|---|---|
| COM-701 | COM-701 | Phase 2 Clinical | Compugen Ltd | Breast Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Head and Neck Neoplasms; Lung Neoplasms; Neoplasms; Ovarian Neoplasms; Solid tumours; Triple Negative Breast Neoplasms | Details |
| PM-1009 | PM1009 | Phase 2 Clinical | Carcinoma, Hepatocellular; Liver Neoplasms; Lung Neoplasms; Neoplasms; Solid tumours | Details | |
| SIM-0348 | SIM-0348 | Phase 1 Clinical | Simcere Pharmaceutical Group Ltd | Neoplasms; Solid tumours | Details |
| GSK-4381562 | SRF-813; GSK-4381562; GSK-4381562A; GSK4381562A; GSK’562 | Phase 1 Clinical | Surface Oncology Inc | Neoplasms; Solid tumours | Details |
| NM1F | NM1F; TGI-2 | Phase 1 Clinical | Hefei TG ImmunoPharma Co Ltd | Colorectal Neoplasms; Melanoma; Ovarian Neoplasms; Solid tumours; Triple Negative Breast Neoplasms | Details |
| SHR-2002 | SHR-2002 | Phase 1 Clinical | Shanghai Hengrui Pharmaceutical Co Ltd, Suzhou Suncadia Biopharmaceuticals Co Ltd | Neoplasms | Details |
| JS-009 | JS009; TAB009; JS-009 | Phase 1 Clinical | Shanghai Junshi Biosciences Co Ltd | Neoplasms; Solid tumours | Details |
- Informations sur la molécule
- Liste de produits
- Informations sur les médicaments cliniques
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