RIPK2
RIPK2 Product List
- Product Category
Protein (1)
- Product Status
Launched (1)
- Species
Human (1)
- Tag
GST Tag (1)
- Conjugate
Unconjugated (1)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|---|
 Human | InsectCells | Human RIPK2 Protein, GST Tag (active enzyme) |  |  |
Total: 1
- 1
RIPK2 Background
Receptor-interacting protein kinase 2 (RIPK2) is a crucial downstream signaling node for NOD1 and NOD2 intracellular pattern recognition receptors. Upon activation, RIPK2 drives NF-κB and MAPK pathways, triggering robust pro-inflammatory cytokine production. Dysregulation of RIPK2 is strongly linked to autoimmune and inflammatory disorders, particularly Crohn's disease, making it a highly attractive target for novel kinase inhibitors and PROTAC degraders.
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