ROBO1 Informations sur la molécule
Molecule Name
Roundabout homolog 1
Alias de la molécule
ROBO1,DUTT1
Drug Development Progress
Nombre de médicaments cliniques0
Nombre de médicaments commercialisés0
Phase de R&D la plus avancéePending
Alias de la cible
DUTT1，Roundabout homolog 1，ROBO1，Roundabout Guidance Receptor 1，Deleted In U Twenty Twenty，Roundabout， Axon Guidance Receptor， Homolog 1 (Drosophila)，Roundabout (Axon Guidance Receptor， Drosophila) Homolog 1，Roundabout， Axon Guidance Receptor， Homolog 1，H-Robo-1，SAX3，FLJ21882
Contexte de la molécule
ROBO1 is a member of the ROBO immunoglobulin superfamily of proteins, and it plays a crucial role in cell motility and migration during embryogenesis and organogenesis. In addition, evidence showed that ROBO1 might drive migration and invasion in malignant cells, such as glioma and breast cancer, which might play a role in cancer aggressiveness. In contrast, some studies suggested that ROBO1 pathways play a key role in tumors by acting as a tumor suppressor, especially in cell invasion.
ROBO1 Liste de produits
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