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Semaphorin 7A

Semaphorin 7A Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
His Tag & Avi Tag (1)
Conjugate
Biotin-labeled (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
SEA-H82E7	Human	HEK293	Biotinylated Human Semaphorin 7A / SEMA7A Protein, His,Avitag™

Total: 1

Semaphorin 7A Background

This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Donaperminogene seltoplasmid (ViroMed)	VM202-Stent; VM202-PAD; pCK-HGF-X7; VM202-DPN; VM-202CAD; VM-202ALS; VM202-RY; VM-202; NL-003; HGF-X7	Phase 3 Clinical	Viromed	Myocardial Ischemia; Diabetic Foot; Charcot-Marie-Tooth Disease; Intermittent Claudication; Myocardial Infarction; Arterial Occlusive Diseases; Peripheral Vascular Diseases; Diabetic Neuropathies; Ischemia; Diabetic peripheral neuropathy; Ulcer; Amyotrophic Lateral Sclerosis; Peripheral Arterial Disease	Details
Fosgonimeton	ATH-1017; NDX-1017	Phase 3 Clinical	M3 Biotechnology	Alzheimer Disease; Lewy Body Disease	Details
Ficlatuzumab	AV-299; SCH-900105	Phase 3 Clinical	Aveo	Multiple Myeloma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Lymphoma; Leukemia, Myeloid, Acute; Lung Neoplasms; Oropharyngeal Neoplasms; Cholangiocarcinoma; Respiratory Tract Neoplasms; Solid tumours; Colonic Neoplasms; Pancreatic Neoplasms; Small Cell Lung Carcinoma; Glioblastoma; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Basal Cell; Head and Neck Neoplasms; Liver Neoplasms	Details
MP-0250	MP-0250	Phase 2 Clinical	Molecular Partners Ag	Neoplasms; Multiple Myeloma; Carcinoma, Non-Small-Cell Lung	Details
YYB-101	NOV-1105; YYB-101	Phase 2 Clinical	Yooyoung	Solid tumours; Colorectal Neoplasms	Details
ATH-1020	ATH-1020	Phase 1 Clinical	Athira Pharma Inc		Details
Microbiome-optimized autologous stem cell therapy (Biotech Holdings)		Clinical	Biotech Holdings	Peripheral Vascular Diseases	Details

Marketed Drug Information

English Name	Research Code	Highest Development Stage	Company	Earliest Brand Name	Earliest Approval Country	Earliest Indication	Earliest Approval Company	Earliest Approval Date	Indication	Clinical Trial
Beperminogene perplasmid	DS-992; AMG-0001; TREAT-HGF; AMG-0001-01	Approved	Anges Mg, Osaka University	Collategene	Japan	Ischemia; Peripheral Arterial Disease	null, Anges Inc	2019-03-01	Arterial Occlusive Diseases; Peripheral Vascular Diseases; Atherosclerosis; Vascular Diseases; Foot Ulcer; Ischemia; Ulcer; Peripheral Arterial Disease	Details