Serpin F1

Serpin F1 Informations sur la molécule

Nom anglais	Pigment epithelium-derived factor	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	2	Alias de la cible	Cell proliferation-inducing gene 35 protein，EPC-1，Serpin Family F Member 1，Proliferation-Inducing Protein 35，OI12，Serpin Peptidase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，PIG35，Serine (Or Cysteine) Proteinase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，OI6，Testis Tissue Sperm-Binding Protein Li 70n，SERPINF1，Serpin F1
Phase de R&D la plus avancée	Phase 3 Clinical

Nom anglais	Pigment epithelium-derived factor
Alias de la cible	Cell proliferation-inducing gene 35 protein，EPC-1，Serpin Family F Member 1，Proliferation-Inducing Protein 35，OI12，Serpin Peptidase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，PIG35，Serine (Or Cysteine) Proteinase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，OI6，Testis Tissue Sperm-Binding Protein Li 70n，SERPINF1，Serpin F1
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	2
Phase de R&D la plus avancée	Phase 3 Clinical

Serpin F1 Liste de produits

Attribut
Protein (1)
Bibliothèque de produits
En ligne (1)
Espèces
Human (1)
Étiquette
His Tag (1)
Marqueur
Unconjugated (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
SE1-H5221	Human	HEK293	Human Serpin F1 / PEDF Protein, His Tag				Ajouter au panier

Quantité totale1

Serpin F1Contexte de la molécule

erpin F1 (SERPINF1) is also known as Pigment epithelium-derived factor (PEDF), Cell proliferation-inducing gene 35 protein (PIG35). Serpin F1 belongs to the serpin family. Serpin F1 is expressed in quiescent cells. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. Endothelial cell migration is inhibited by SERPINF1/ PEDF. PEDF / SERPINF1 suppresses retinal neovascularization and endothelial cell proliferation. PEDF is also responsible for apoptosis of endothelial cells either through the p38 MAPK pathway or through the FAS/FASL pathway. PEDF also displays neurotrophic functions.

Serpin F1Alias de la molécule

SERPINF1,Serpin F1,PEDF,PIG35,EPC-1

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
BRM-421	BRM-421	Phase 3 Clinical	Brim Biotechnology Co Ltd	Dry Eye Syndromes; Keratoconjunctivitis Sicca; Xerophthalmia	Details
DVC1-0401	DVC1-0401	Phase 2 Clinical	Id Pharma, Kyushu University	Retinitis Pigmentosa	Details