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Page d'accueilToutes les moléculesSLAMF7
SLAMF7
SLAMF7 Informations sur la molécule
| Nom anglais | SLAM family member 7 | Nombre de médicaments commercialisés | 1 |
| Nombre de médicaments cliniques | 8 | Alias de la cible | CS1，UNQ576/PRO1138，SLAMF7，Novel Ly9，SLAM Family Member 7，Membrane Protein FOAP-12，CD2 Subset 1，Protein 19A，CRACC，CD2-Like Receptor Activating Cytotoxic Cells，CD2-Like Receptor-Activating Cytotoxic Cells，19A24 Protein，CD319，19A，CD319 Antigen，Novel LY9 (Lymphocyte Antigen 9) Like Protein |
| Phase de R&D la plus avancée | Approved | ||
| Nom anglais | SLAM family member 7 |
| Alias de la cible | CS1，UNQ576/PRO1138，SLAMF7，Novel Ly9，SLAM Family Member 7，Membrane Protein FOAP-12，CD2 Subset 1，Protein 19A，CRACC，CD2-Like Receptor Activating Cytotoxic Cells，CD2-Like Receptor-Activating Cytotoxic Cells，19A24 Protein，CD319，19A，CD319 Antigen，Novel LY9 (Lymphocyte Antigen 9) Like Protein |
| Nombre de médicaments commercialisés | 1 |
| Nombre de médicaments cliniques | 8 |
| Phase de R&D la plus avancée | Approved |
SLAMF7 Liste de produits
- Attribut
Protein (8)
- Bibliothèque de produits
En ligne (8)
- Espèces
Human (6)Mouse (1)Rhesus macaque (1)
- Étiquette
His Tag (5)Fc Tag (1)His Tag & Avi Tag (1)Mouse IgG Fc Tag (1)
- Marqueur
Unconjugated (4)Biotin-labeled (1)FITC Labeled (1)PE Labeled (2)
| Numéro de produit | Espèces | Système d'expression | Description du produit | Structure protéique | Pureté | Caractéristiques | Pré-commande/Commande |
|---|---|---|---|---|---|---|---|
HOT SL7-H5225 |  Human | HEK293 | Human SLAMF7 / CRACC / CD319 Protein, His Tag, low Endotoxin (MALS verified) |  |  |  |  Ajouter au panier |
HOT SL7-H82E0 | Human | HEK293 | Biotinylated Human SLAMF7 / CRACC / CD319 Protein, Avitag™,His Tag (MALS verified) |  | | | Ajouter au panier |
HOT SL7-HP2H3 | Human | HEK293 | PE-Labeled Human SLAMF7 / CRACC / CD319 Protein, His Tag (Site-specific conjugation) |  |  | Ajouter au panier | |
HOT SL7-HP2H6 | Human | HEK293 | PE-Labeled Human SLAMF7 / CRACC / CD319 Protein, His TagStar Staining | Ajouter au panier | |||
HOT SL7-R52H7 |  Rhesus macaque | HEK293 | Rhesus macaque SLAMF7 / CRACC / CD319 Protein, His Tag (MALS verified) |  | | Ajouter au panier | |
| Human | HEK293 | Human SLAMF7 / CRACC / CD319 Protein, Fc Tag |  | | | Ajouter au panier | |
| Human | HEK293 | FITC-Labeled Human SLAMF7 / CRACC / CD319 Protein, His Tag |  | | | Ajouter au panier | |
 Mouse | HEK293 | Mouse SLAMF7 / CRACC / CD319 Protein, Mouse IgG2a Fc Tag, low endotoxin |  | | Ajouter au panier |
Quantité totale8
- 1
SLAMF7Contexte de la molécule
SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 of SLAMF7 does not mediate any NK cell activation.
SLAMF7Alias de la molécule
SLAMF7,CD319,CS1,CRACC,19A,FOAP-12
Informations sur les médicaments cliniques
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Indication | Essai clinique |
|---|---|---|---|---|---|
| SLAMF7 CAR-T cell therapy (Wuerzburg University Hospital) | Phase 2 Clinical | University Hospital Würzburg | Multiple Myeloma | Details | |
| dual anti-CS-1/anti-BCMA CAR T-cell therapy (Wuhan Sian Medical Technology) | Phase 1 Clinical | Wuhan Sian Biotechnology Co Ltd | Multiple Myeloma | Details | |
| BCMA-CS1 cCAR T-cell therapy | Phase 1 Clinical | iCell Gene Therapeutics LLC | Multiple Myeloma | Details | |
| SA102-CAR-T | SA-102; SA102 | Phase 1 Clinical | Wuhan Sian Biotechnology Co Ltd | Multiple Myeloma | Details |
| WS-CART-CS1 | WS-CART-CS1 | Phase 1 Clinical | Paula C. & Rodger O. Riney Blood Cancer Research, Washington University School Of Medicine | Multiple Myeloma | Details |
| MB-104 | MB-104; MB-105; MB-104 CS1 CAR; MB-105 PSCA CAR | Phase 1 Clinical | City Of Hope National Medical Center | Glioblastoma; Multiple Myeloma; Pancreatic Neoplasms; Prostatic Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms | Details |
| CS1 Targeted CAR T-cells (Yake Biotechnology) | Phase 1 Clinical | Shanghai YaKe Biotechnology Co Ltd | Multiple Myeloma | Details | |
| CD319 chimeric antigen T cell therapy (Wuhan Bio Raid Biotechnology) | Clinical | Wuhan BioRaid Biotechnology Co Ltd | Hematologic Neoplasms | Details |
Informations sur les médicaments commercialisés
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Plus ancien nom de marque | Pays d'approbation le plus ancien | Indication la plus ancienne | Société d'approbation la plus ancienne | Date d'approbation la plus ancienne | Indication | Essai clinique |
|---|---|---|---|---|---|---|---|---|---|---|
| Elotuzumab | PDL-063; HuLuc-63; BMS-901608 | Approved | Abbvie Inc, Bristol-Myers Squibb Company | Empliciti | United States | Multiple Myeloma | Bristol-Myers Squibb Company | 2015-11-30 | Hematologic Neoplasms; Hematopoietic stem cell transplantation (HSCT); Leukemia, Plasma Cell; Lymphoma; Multiple Myeloma; Polycythemia Vera; Primary Myelofibrosis; Smoldering Multiple Myeloma; Thrombocythemia, Essential | Details |
- Informations sur la molécule
- Liste de produits
- Informations sur les médicaments commercialisés
- Informations sur les médicaments cliniques
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