SLC1A2

SLC1A2 Informations sur la molécule

Nom anglais	Excitatory amino acid transporter 2	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	2	Alias de la cible	GLT1，Glutamate/aspartate transporter II，Sodium-dependent glutamate/aspartate transporter 2，Solute carrier family 1 member 2，SLC1A2，EAAT2
Phase de R&D la plus avancée	Phase 2 Clinical

Nom anglais	Excitatory amino acid transporter 2
Alias de la cible	GLT1，Glutamate/aspartate transporter II，Sodium-dependent glutamate/aspartate transporter 2，Solute carrier family 1 member 2，SLC1A2，EAAT2
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	2
Phase de R&D la plus avancée	Phase 2 Clinical

SLC1A2 Liste de produits

Attribut
Protein (1)
Bibliothèque de produits
En ligne (1)
Espèces
Human (1)
Étiquette
His Tag & Flag Tag (1)
Marqueur
Unconjugated (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
SL2-H52D6	Human	HEK293	Human SLC1A2 Protein, Flag,His Tag (Detergent)				Ajouter au panier

Quantité totale1

SLC1A2Contexte de la molécule

This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2017]

SLC1A2Alias de la molécule

DEE41, EAAT2, EIEE41, GLT-1, GLT1, HBGT

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
[18F]RP-115	[18F]RP-115	Phase 2 Clinical	Rio pharmaceuticals Inc	Alzheimer Disease; Dementia; Frontotemporal Dementia	Details
iQ-007	iQ-007	Phase 1 Clinical	iQure Pharma Inc	Drug Resistant Epilepsy; Epilepsies, Partial; Epilepsy; Neuralgia	Details

Avis sur les produits

E***a2026-04-29
0Mettre un like
Human SLC1A2 Protein, Flag,His Tag (Detergent)
We used this a POC and it worked in some assays where we got informative data. It is great to see detergent-stabilized proteins becoming more available commercially.