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Stathmin 1

Stathmin 1 Overview

English Name	Stathmin	Approved Drugs	0
Drugs in Clinical Trials	2	Target Synonym	Protein Pr22，Phosphoprotein p19，LAP18，C1orf215，STMN1，Stathmin 1，Oncoprotein 18，Leukemia-Associated Phosphoprotein P18，Stathmin 1/Oncoprotein 18，Metablastin，Prosolin，Chromosome 1 Open Reading Frame 215，Testicular Tissue Protein Li 189，Transmembrane Protein C1orf215，Phosphoprotein 19，Stathmin，PP17，PR22，Op18，Pp19，Lag，SMN，FLJ32206
Highest Development Stage	Phase 1 Clinical

English Name	Stathmin
Target Synonym	Protein Pr22，Phosphoprotein p19，LAP18，C1orf215，STMN1，Stathmin 1，Oncoprotein 18，Leukemia-Associated Phosphoprotein P18，Stathmin 1/Oncoprotein 18，Metablastin，Prosolin，Chromosome 1 Open Reading Frame 215，Testicular Tissue Protein Li 189，Transmembrane Protein C1orf215，Phosphoprotein 19，Stathmin，PP17，PR22，Op18，Pp19，Lag，SMN，FLJ32206
Approved Drugs	0
Drugs in Clinical Trials	2
Highest Development Stage	Phase 1 Clinical

Stathmin 1 Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
His Tag (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
ST1-H5149	Human	E. coli	Human Stathmin 1 / STMN1 Protein, His Tag

Total: 1

Stathmin 1 Background

Stathmin (STMN1), a member of the stathmin family, is also known as Leukemia-associated phosphoprotein p18, Oncoprotein 18 (Op18), Phosphoprotein p19 (pp19), Protein Pr22 and pp17, which contains one SLD (stathmin-like) domain. The function of STMN1 as an important regulatory protein of microtubule dynamics has been well-characterized. Stathmin (STMN1) interacts with two molecules of dimeric α,β-tubulin to form a tight ternary complex called the T2S complex.One mole of STMN1 binds to two moles of tubulin dimers through the stathmin-like domain (SLD).When STMN1 sequesters tubulin into the T2S complex, tubulin becomes non-polymerizable. Without tubulin polymerization, there is no microtubule assembly.STMN1 also promotes microtubule disassembly by acting directly on the microtubule ends.