Stathmin 1

Stathmin 1 Informations sur la molécule

Nom anglais	Stathmin	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	2	Alias de la cible	Protein Pr22，Phosphoprotein p19，LAP18，C1orf215，STMN1，Stathmin 1，Oncoprotein 18，Leukemia-Associated Phosphoprotein P18，Stathmin 1/Oncoprotein 18，Metablastin，Prosolin，Chromosome 1 Open Reading Frame 215，Testicular Tissue Protein Li 189，Transmembrane Protein C1orf215，Phosphoprotein 19，Stathmin，PP17，PR22，Op18，Pp19，Lag，SMN，FLJ32206
Phase de R&D la plus avancée	Phase 1 Clinical

Nom anglais	Stathmin
Alias de la cible	Protein Pr22，Phosphoprotein p19，LAP18，C1orf215，STMN1，Stathmin 1，Oncoprotein 18，Leukemia-Associated Phosphoprotein P18，Stathmin 1/Oncoprotein 18，Metablastin，Prosolin，Chromosome 1 Open Reading Frame 215，Testicular Tissue Protein Li 189，Transmembrane Protein C1orf215，Phosphoprotein 19，Stathmin，PP17，PR22，Op18，Pp19，Lag，SMN，FLJ32206
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	2
Phase de R&D la plus avancée	Phase 1 Clinical

Stathmin 1 Liste de produits

Attribut
Protein (1)
Bibliothèque de produits
En ligne (1)
Espèces
Human (1)
Étiquette
His Tag (1)
Marqueur
Unconjugated (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
ST1-H5149	Human	E. coli	Human Stathmin 1 / STMN1 Protein, His Tag				Ajouter au panier

Quantité totale1

Stathmin 1Contexte de la molécule

Stathmin (STMN1), a member of the stathmin family, is also known as Leukemia-associated phosphoprotein p18, Oncoprotein 18 (Op18), Phosphoprotein p19 (pp19), Protein Pr22 and pp17, which contains one SLD (stathmin-like) domain. The function of STMN1 as an important regulatory protein of microtubule dynamics has been well-characterized. Stathmin (STMN1) interacts with two molecules of dimeric α,β-tubulin to form a tight ternary complex called the T2S complex.One mole of STMN1 binds to two moles of tubulin dimers through the stathmin-like domain (SLD).When STMN1 sequesters tubulin into the T2S complex, tubulin becomes non-polymerizable. Without tubulin polymerization, there is no microtubule assembly.STMN1 also promotes microtubule disassembly by acting directly on the microtubule ends.