TACI

TACI Informations sur la molécule

Nom anglais	Tumor necrosis factor receptor superfamily member 13B	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0	Alias de la cible	Transmembrane activator and CAML interactor，CD267，TACI
Phase de R&D la plus avancée	Preclinical

Nom anglais	Tumor necrosis factor receptor superfamily member 13B
Alias de la cible	Transmembrane activator and CAML interactor，CD267，TACI
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0
Phase de R&D la plus avancée	Preclinical

TACI Liste de produits

Attribut
Protein (6)Cell (1)
Bibliothèque de produits
En ligne (7)
Espèces
Human (7)
Étiquette
Fc Tag & Avi Tag (1)Fc Tag (2)His Tag (1)- (2)His Tag & Avi Tag (1)
Marqueur
Biotin-labeled (3)Unconjugated (3)- (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT TAI-H52H3	Human	HEK293	Human TACI / TNFRSF13B Protein, His Tag, low endotoxin	Ajouter au panier
CHEK-ATF197	Human	HEK293	Human TACI (Luc) HEK293 Reporter Cell	Ajouter au panier
TAI-H5253	Human	HEK293	Human TACI / TNFRSF13B (R119A, R122A) Protein, Fc Tag (MALS verified)	Ajouter au panier
TAI-H5254	Human	HEK293	Human TACI / TNFRSF13B Protein, Fc Tag (HPLC verified)	Ajouter au panier
TAI-H82E3	Human	HEK293	Biotinylated Human TACI / TNFRSF13B Protein, His,Avitag™ (MALS verified)	Ajouter au panier
TAI-H82F6	Human	HEK293	Biotinylated Human TACI / TNFRSF13B Protein, Fc,Avitag™	Ajouter au panier
TAL-H82F3	Human	HEK293	Biotinylated Human TACI / TNFRSF13B Protein, Fc,Avitag™ (MALS verified)	Ajouter au panier

Quantité totale7

TACIContexte de la molécule

Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B). It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. The present study demonstrated that, in NSCLC, a proliferation-inducing ligand (APRIL), B-cell maturation antigen (BCMA)and transmembrane activator and CAML interactor (TACI) proteins are abnormally expressed by immunohistochemistry, reverse transcription-quantitative polymerase chain reaction and western blotting. In addition, the expression of APRIL, BCMA and TACI were observed to be involved in extracellular signal-regulated kinase (ERK)1/2 activation in A549 cells.