TDP-43

TDP-43 Informations sur la molécule

Nom anglais	TAR DNA binding protein 43	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	6	Alias de la cible	TAR DNA-binding protein 43，TARDBP，TAR DNA Binding Protein，TDP43，TAR DNA-Binding Protein-43，ALS10
Phase de R&D la plus avancée	Phase 3 Clinical

Nom anglais	TAR DNA binding protein 43
Alias de la cible	TAR DNA-binding protein 43，TARDBP，TAR DNA Binding Protein，TDP43，TAR DNA-Binding Protein-43，ALS10
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	6
Phase de R&D la plus avancée	Phase 3 Clinical

TDP-43 Liste de produits

Attribut
Protein (1)
Bibliothèque de produits
En ligne (1)
Espèces
Human (1)
Étiquette
His Tag (1)
Marqueur
Unconjugated (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
AI Compatible TD3-H5145	Human	E. coli	Human TDP-43 Protein, His Tag				Ajouter au panier

Quantité totale1

TDP-43Contexte de la molécule

TDP-43, the transactive response (TAR)-DNA binding Protein with a molecular weight of 43 KDa is encoded by TARDBP gene that located at the chromosome 1. It is a RNA/DNA binding protein that structurally resembles a typical hnRNP protein family member. involved in transcriptional regulation and RNA processing. It is linked to sporadic and familial amyotrophic lateral sclerosis and frontotemporal lobar degeneration. TDP-43 is predominantly nuclear, but it translocates to the cytoplasm under pathological conditions. Cytoplasmic accumulation, phosphorylation, ubiquitination and truncation of TDP-43 are the main hallmarks of TDP-43 proteinopathies.

TDP-43Alias de la molécule

TAR DNA-binding protein 43

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
Monepantel	PPL-1; NUZ-001	Phase 3 Clinical	Pitney Pharmaceuticals Pty Ltd	Amyotrophic Lateral Sclerosis; Motor Neuron Disease; Neoplasms	Details
nL-TARD-001	nL-TARD-001	Phase 2 Clinical	N-Lorem Foundation	Amyotrophic Lateral Sclerosis	Details
AMDX-2011P	AMDX2011P; AMDX-2011P	Phase 2 Clinical	Amydis Inc	Alzheimer Disease; Amyotrophic Lateral Sclerosis; Cerebral Amyloid Angiopathy; Glaucoma, Open-Angle; Parkinson Disease	Details
VTx-002 (VectorY)	VTx-002	Phase 2 Clinical	VectorY BV	Amyotrophic Lateral Sclerosis	Details
CTx-1000	CTx1000; CTx-1000	Phase 1 Clinical	Celosia Therapeutics Pty Ltd	Amyotrophic Lateral Sclerosis	Details
AB-14	AB-14	Phase 1 Clinical	Autotac Bio Inc	Amyotrophic Lateral Sclerosis	Details

Avis sur les produits

n***l2026-04-14
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Human TDP-43 Protein, His Tag
We ordered Human TDP-43 Protein, His Tag and was very happy with the fast shipping to get our project going. Customer service was very helpful on the phone before I placed my order online.